Ikura M - Search Results

1

Multiplexed Real-Time NMR GTPase Assay for Simultaneous Monitoring of Multiple Guanine Nucleotide Exchange Factor Activities from Human Cancer Cells and Organoids.

Gebregiworgis T, Marshall CB, Nishikawa T, Radulovich N, Sandí MJ, Fang Z, Rottapel R, Tsao MS, Ikura M. Gebregiworgis T, et al. Among authors: ikura m. J Am Chem Soc. 2018 Apr 4;140(13):4473-4476. doi: 10.1021/jacs.7b13703. Epub 2018 Mar 22. J Am Chem Soc. 2018. PMID: 29543440

2

The ATCUN domain as a probe of intermolecular interactions: application to calmodulin-peptide complexes.

Mal TK, Ikura M, Kay LE. Mal TK, et al. Among authors: ikura m. J Am Chem Soc. 2002 Nov 27;124(47):14002-3. doi: 10.1021/ja028109p. J Am Chem Soc. 2002. PMID: 12440892

3

Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53.

Wang F, Marshall CB, Yamamoto K, Li GY, Plevin MJ, You H, Mak TW, Ikura M. Wang F, et al. Among authors: ikura m. J Mol Biol. 2008 Dec 19;384(3):590-603. doi: 10.1016/j.jmb.2008.09.025. Epub 2008 Sep 18. J Mol Biol. 2008. PMID: 18824006

4

Characterization of a conserved "threonine clasp" in CAP-Gly domains: role of a functionally critical OH/pi interaction in protein recognition.

Plevin MJ, Hayashi I, Ikura M. Plevin MJ, et al. Among authors: ikura m. J Am Chem Soc. 2008 Nov 12;130(45):14918-9. doi: 10.1021/ja805576n. Epub 2008 Oct 21. J Am Chem Soc. 2008. PMID: 18937471

5

Characterization of the intrinsic and TSC2-GAP-regulated GTPase activity of Rheb by real-time NMR.

Marshall CB, Ho J, Buerger C, Plevin MJ, Li GY, Li Z, Ikura M, Stambolic V. Marshall CB, et al. Among authors: ikura m. Sci Signal. 2009 Jan 27;2(55):ra3. doi: 10.1126/scisignal.2000029. Sci Signal. 2009. PMID: 19176517

6

Synergistic interplay between promoter recognition and CBP/p300 coactivator recruitment by FOXO3a.

Wang F, Marshall CB, Li GY, Yamamoto K, Mak TW, Ikura M. Wang F, et al. Among authors: ikura m. ACS Chem Biol. 2009 Dec 18;4(12):1017-27. doi: 10.1021/cb900190u. ACS Chem Biol. 2009. PMID: 19821614

7

Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics.

Mazhab-Jafari MT, Marshall CB, Smith M, Gasmi-Seabrook GM, Stambolic V, Rottapel R, Neel BG, Ikura M. Mazhab-Jafari MT, et al. Among authors: ikura m. J Biol Chem. 2010 Feb 19;285(8):5132-6. doi: 10.1074/jbc.C109.064766. Epub 2009 Dec 14. J Biol Chem. 2010. PMID: 20018863 Free PMC article.

8

Real-time NMR study of guanine nucleotide exchange and activation of RhoA by PDZ-RhoGEF.

Gasmi-Seabrook GM, Marshall CB, Cheung M, Kim B, Wang F, Jang YJ, Mak TW, Stambolic V, Ikura M. Gasmi-Seabrook GM, et al. Among authors: ikura m. J Biol Chem. 2010 Feb 19;285(8):5137-45. doi: 10.1074/jbc.M109.064691. Epub 2009 Dec 17. J Biol Chem. 2010. PMID: 20018869 Free PMC article.

9

Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition.

Meiri D, Marshall CB, Greeve MA, Kim B, Balan M, Suarez F, Bakal C, Wu C, Larose J, Fine N, Ikura M, Rottapel R. Meiri D, et al. Among authors: ikura m. Mol Cell. 2012 Mar 9;45(5):642-55. doi: 10.1016/j.molcel.2012.01.027. Mol Cell. 2012. PMID: 22405273 Free article.

10

Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.

Wang F, Marshall CB, Yamamoto K, Li GY, Gasmi-Seabrook GM, Okada H, Mak TW, Ikura M. Wang F, et al. Among authors: ikura m. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6078-83. doi: 10.1073/pnas.1119073109. Epub 2012 Apr 2. Proc Natl Acad Sci U S A. 2012. PMID: 22474372 Free PMC article.

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