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Embelin inhibits pancreatic cancer progression by directly inducing cancer cell apoptosis and indirectly restricting IL-6 associated inflammatory and immune suppressive cells.
Peng M, Huang B, Zhang Q, Fu S, Wang D, Cheng X, Wu X, Xue Z, Zhang L, Zhang D, Da Y, Dai Y, Yang Q, Yao Z, Qiao L, Zhang R. Peng M, et al. Among authors: wu x. Cancer Lett. 2014 Nov 28;354(2):407-16. doi: 10.1016/j.canlet.2014.08.011. Epub 2014 Aug 13. Cancer Lett. 2014. PMID: 25128650
Identifying the E2F3-MEX3A-KLF4 signaling axis that sustains cancer cells in undifferentiated and proliferative state.
Yang X, Li G, Tian Y, Wang X, Xu J, Liu R, Deng M, Shao C, Pan Y, Wu X, Li M, Zhang C, Liu R, Qin J, Zhang C, Liu Z, Wu X, Plikus MV, Lengner CJ, Zheng Z, Lv C, Yu Z. Yang X, et al. Among authors: wu x. Theranostics. 2022 Sep 25;12(16):6865-6882. doi: 10.7150/thno.76619. eCollection 2022. Theranostics. 2022. PMID: 36276637 Free PMC article.
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