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Selection of appropriate tumour data sets for Benchmark Dose Modelling (BMD) and derivation of a Margin of Exposure (MoE) for substances that are genotoxic and carcinogenic: considerations of biological relevance of tumour type, data quality and uncertainty assessment.
Edler L, Hart A, Greaves P, Carthew P, Coulet M, Boobis A, Williams GM, Smith B. Edler L, et al. Among authors: smith b. Food Chem Toxicol. 2014 Aug;70:264-89. doi: 10.1016/j.fct.2013.10.030. Epub 2013 Oct 29. Food Chem Toxicol. 2014. PMID: 24176677 Free article.
A quantitative in silico model for predicting skin sensitization using a nearest neighbours approach within expert-derived structure-activity alert spaces.
Canipa SJ, Chilton ML, Hemingway R, Macmillan DS, Myden A, Plante JP, Tennant RE, Vessey JD, Steger-Hartmann T, Gould J, Hillegass J, Etter S, Smith BPC, White A, Sterchele P, De Smedt A, O'Brien D, Parakhia R. Canipa SJ, et al. J Appl Toxicol. 2017 Aug;37(8):985-995. doi: 10.1002/jat.3448. Epub 2017 Feb 28. J Appl Toxicol. 2017. PMID: 28244128
Assessment of the genotoxic potential of mintlactone.
Thakkar Y, Moustakas H, Api AM, Smith B, Williams G, Greim H, Eisenbrand G, Dekant W. Thakkar Y, et al. Among authors: smith b. Food Chem Toxicol. 2022 Jan;159:112659. doi: 10.1016/j.fct.2021.112659. Epub 2021 Nov 19. Food Chem Toxicol. 2022. PMID: 34801651
The BlueScreen HC assay to predict the genotoxic potential of fragrance materials.
Thakkar Y, Joshi K, Hickey C, Wahler J, Wall B, Etter S, Smith B, Griem P, Tate M, Jones F, Oudraogo G, Pfuhler S, Choi C, Williams G, Greim H, Eisenbrand G, Dekant W, Api AM. Thakkar Y, et al. Among authors: smith b. Mutagenesis. 2022 Apr 2;37(1):13-23. doi: 10.1093/mutage/geac004. Mutagenesis. 2022. PMID: 35302169 Free PMC article.
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