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Amelioration of Head and Neck Radiation-Induced Mucositis and Distant Marrow Suppression in Fanca-/- and Fancg-/- Mice by Intraoral Administration of GS-Nitroxide (JP4-039).
Willis J, Epperly MW, Fisher R, Zhang X, Shields D, Hou W, Wang H, Li S, Wipf P, Parmar K, Guinan E, Steinman J, Greenberger JS. Willis J, et al. Among authors: parmar k. Radiat Res. 2018 Jun;189(6):560-578. doi: 10.1667/RR14878.1. Epub 2018 Mar 27. Radiat Res. 2018. PMID: 29584588 Free PMC article.
Bactericidal/permeability-increasing protein (rBPI21) and fluoroquinolone mitigate radiation-induced bone marrow aplasia and death.
Guinan EC, Barbon CM, Kalish LA, Parmar K, Kutok J, Mancuso CJ, Stoler-Barak L, Suter EE, Russell JD, Palmer CD, Gallington LC, Voskertchian A, Vergilio JA, Cole G, Zhu K, D'Andrea A, Soiffer R, Weiss JP, Levy O. Guinan EC, et al. Among authors: parmar k. Sci Transl Med. 2011 Nov 23;3(110):110ra118. doi: 10.1126/scitranslmed.3003126. Sci Transl Med. 2011. PMID: 22116933 Free PMC article. Clinical Trial.
Intraoral Mitochondrial-Targeted GS-Nitroxide, JP4-039, Radioprotects Normal Tissue in Tumor-Bearing Radiosensitive Fancd2(-/-) (C57BL/6) Mice.
Shinde A, Berhane H, Rhieu BH, Kalash R, Xu K, Goff J, Epperly MW, Franicola D, Zhang X, Dixon T, Shields D, Wang H, Wipf P, Parmar K, Guinan E, Kagan V, Tyurin V, Ferris RL, Zhang X, Li S, Greenberger JS. Shinde A, et al. Among authors: parmar k. Radiat Res. 2016 Feb;185(2):134-50. doi: 10.1667/RR14035.1. Epub 2016 Jan 20. Radiat Res. 2016. PMID: 26789701 Free PMC article.
A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2.
Dubois EL, Guitton-Sert L, Béliveau M, Parmar K, Chagraoui J, Vignard J, Pauty J, Caron MC, Coulombe Y, Buisson R, Jacquet K, Gamblin C, Gao Y, Laprise P, Lebel M, Sauvageau G, D d'Andrea A, Masson JY. Dubois EL, et al. Among authors: parmar k. Nucleic Acids Res. 2019 Aug 22;47(14):7532-7547. doi: 10.1093/nar/gkz514. Nucleic Acids Res. 2019. PMID: 31219578 Free PMC article.
MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia.
Rodríguez A, Zhang K, Färkkilä A, Filiatrault J, Yang C, Velázquez M, Furutani E, Goldman DC, García de Teresa B, Garza-Mayén G, McQueen K, Sambel LA, Molina B, Torres L, González M, Vadillo E, Pelayo R, Fleming WH, Grompe M, Shimamura A, Hautaniemi S, Greenberger J, Frías S, Parmar K, D'Andrea AD. Rodríguez A, et al. Among authors: parmar k. Cell Stem Cell. 2021 Jan 7;28(1):33-47.e8. doi: 10.1016/j.stem.2020.09.004. Epub 2020 Sep 29. Cell Stem Cell. 2021. PMID: 32997960 Free PMC article.
Inhibition of TGFβ1 and TGFβ3 promotes hematopoiesis in Fanconi anemia.
Rodríguez A, Yang C, Furutani E, García de Teresa B, Velázquez M, Filiatrault J, Sambel LA, Phan T, Flores-Guzmán P, Sánchez S, Monsiváis Orozco A, Mayani H, Bolukbasi OV, Färkkilä A, Epperly M, Greenberger J, Shimamura A, Frías S, Grompe M, Parmar K, D'Andrea AD. Rodríguez A, et al. Among authors: parmar k. Exp Hematol. 2021 Jan;93:70-84.e4. doi: 10.1016/j.exphem.2020.11.002. Epub 2020 Nov 7. Exp Hematol. 2021. PMID: 33166613 Free PMC article.
TGFβ pathway is required for viable gestation of Fanconi anemia embryos.
Rodríguez A, Epperly M, Filiatrault J, Velázquez M, Yang C, McQueen K, Sambel LA, Nguyen H, Iyer DR, Juárez U, Ayala-Zambrano C, Martignetti DB, Frías S, Fisher R, Parmar K, Greenberger JS, D'Andrea AD. Rodríguez A, et al. Among authors: parmar k. PLoS Genet. 2022 Nov 28;18(11):e1010459. doi: 10.1371/journal.pgen.1010459. eCollection 2022 Nov. PLoS Genet. 2022. PMID: 36441774 Free PMC article.
439 results