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Efficient In Vivo Liver-Directed Gene Editing Using CRISPR/Cas9.
Singh K, Evens H, Nair N, Rincón MY, Sarcar S, Samara-Kuko E, Chuah MK, VandenDriessche T. Singh K, et al. Mol Ther. 2018 May 2;26(5):1241-1254. doi: 10.1016/j.ymthe.2018.02.023. Epub 2018 Mar 6. Mol Ther. 2018. PMID: 29599079 Free PMC article.
Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells.
Dastidar S, Ardui S, Singh K, Majumdar D, Nair N, Fu Y, Reyon D, Samara E, Gerli MFM, Klein AF, De Schrijver W, Tipanee J, Seneca S, Tulalamba W, Wang H, Chai YC, In't Veld P, Furling D, Tedesco FS, Vermeesch JR, Joung JK, Chuah MK, VandenDriessche T. Dastidar S, et al. Among authors: singh k. Nucleic Acids Res. 2018 Sep 19;46(16):8275-8298. doi: 10.1093/nar/gky548. Nucleic Acids Res. 2018. PMID: 29947794 Free PMC article.
In utero CRISPR-mediated therapeutic editing of metabolic genes.
Rossidis AC, Stratigis JD, Chadwick AC, Hartman HA, Ahn NJ, Li H, Singh K, Coons BE, Li L, Lv W, Zoltick PW, Alapati D, Zacharias W, Jain R, Morrisey EE, Musunuru K, Peranteau WH. Rossidis AC, et al. Among authors: singh k. Nat Med. 2018 Oct;24(10):1513-1518. doi: 10.1038/s41591-018-0184-6. Epub 2018 Oct 8. Nat Med. 2018. PMID: 30297903 Free PMC article.
Hemophilia Gene Therapy: The End of the Beginning?
De Wolf D, Singh K, Chuah MK, VandenDriessche T. De Wolf D, et al. Among authors: singh k. Hum Gene Ther. 2023 Sep;34(17-18):782-792. doi: 10.1089/hum.2023.112. Hum Gene Ther. 2023. PMID: 37672530 Review.
In utero gene editing for monogenic lung disease.
Alapati D, Zacharias WJ, Hartman HA, Rossidis AC, Stratigis JD, Ahn NJ, Coons B, Zhou S, Li H, Singh K, Katzen J, Tomer Y, Chadwick AC, Musunuru K, Beers MF, Morrisey EE, Peranteau WH. Alapati D, et al. Among authors: singh k. Sci Transl Med. 2019 Apr 17;11(488):eaav8375. doi: 10.1126/scitranslmed.aav8375. Sci Transl Med. 2019. PMID: 30996081 Free PMC article.
In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease.
Bose SK, White BM, Kashyap MV, Dave A, De Bie FR, Li H, Singh K, Menon P, Wang T, Teerdhala S, Swaminathan V, Hartman HA, Jayachandran S, Chandrasekaran P, Musunuru K, Jain R, Frank DB, Zoltick P, Peranteau WH. Bose SK, et al. Among authors: singh k. Nat Commun. 2021 Jul 13;12(1):4291. doi: 10.1038/s41467-021-24443-8. Nat Commun. 2021. PMID: 34257302 Free PMC article.
9,965 results