Hyman BT - Search Results

1

Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation.

Liao F, Li A, Xiong M, Bien-Ly N, Jiang H, Zhang Y, Finn MB, Hoyle R, Keyser J, Lefton KB, Robinson GO, Serrano JR, Silverman AP, Guo JL, Getz J, Henne K, Leyns CE, Gallardo G, Ulrich JD, Sullivan PM, Lerner EP, Hudry E, Sweeney ZK, Dennis MS, Hyman BT, Watts RJ, Holtzman DM. Liao F, et al. Among authors: hyman bt. J Clin Invest. 2018 May 1;128(5):2144-2155. doi: 10.1172/JCI96429. Epub 2018 Mar 30. J Clin Invest. 2018. PMID: 29600961 Free PMC article.

2

Lack of allelic imbalance in APOE epsilon3/4 brain mRNA expression in Alzheimer's disease.

Growdon WB, Cheung BS, Hyman BT, Rebeck GW. Growdon WB, et al. Among authors: hyman bt. Neurosci Lett. 1999 Sep 10;272(2):83-6. doi: 10.1016/s0304-3940(99)00557-1. Neurosci Lett. 1999. PMID: 10507547

3

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

Holtzman DM, Fagan AM, Mackey B, Tenkova T, Sartorius L, Paul SM, Bales K, Ashe KH, Irizarry MC, Hyman BT. Holtzman DM, et al. Among authors: hyman bt. Ann Neurol. 2000 Jun;47(6):739-47. Ann Neurol. 2000. PMID: 10852539

4

Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Abeta aggregation.

Cho HS, Hyman BT, Greenberg SM, Rebeck GW. Cho HS, et al. Among authors: hyman bt. J Neuropathol Exp Neurol. 2001 Apr;60(4):342-9. doi: 10.1093/jnen/60.4.342. J Neuropathol Exp Neurol. 2001. PMID: 11305869

5

Multiphoton microscopy and amyloid angiopathy.

Christie R, Kimchi E, Kajdasz S, Bacskai B, Hyman BT. Christie R, et al. Among authors: hyman bt. Amyloid. 2001 Jul;8 Suppl 1:48-50. Amyloid. 2001. PMID: 11676290

6

Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.

Bacskai BJ, Kajdasz ST, McLellan ME, Games D, Seubert P, Schenk D, Hyman BT. Bacskai BJ, et al. Among authors: hyman bt. J Neurosci. 2002 Sep 15;22(18):7873-8. doi: 10.1523/JNEUROSCI.22-18-07873.2002. J Neurosci. 2002. PMID: 12223540 Free PMC article.

7

APOE epsilon 3/ epsilon 4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer's disease diagnosis.

Fukumoto H, Ingelsson M, Gårevik N, Wahlund LO, Nukina N, Yaguchi Y, Shibata M, Hyman BT, Rebeck GW, Irizarry MC. Fukumoto H, et al. Among authors: hyman bt. Exp Neurol. 2003 Sep;183(1):249-53. doi: 10.1016/s0014-4886(03)00088-8. Exp Neurol. 2003. PMID: 12957508

8

Apolipoprotein E modulates gamma-secretase cleavage of the amyloid precursor protein.

Irizarry MC, Deng A, Lleo A, Berezovska O, Von Arnim CA, Martin-Rehrmann M, Manelli A, LaDu MJ, Hyman BT, Rebeck GW. Irizarry MC, et al. Among authors: hyman bt. J Neurochem. 2004 Sep;90(5):1132-43. doi: 10.1111/j.1471-4159.2004.02581.x. J Neurochem. 2004. PMID: 15312168 Free article.

9

Neuronal structure is altered by amyloid plaques.

Spires TL, Hyman BT. Spires TL, et al. Among authors: hyman bt. Rev Neurosci. 2004;15(4):267-78. doi: 10.1515/revneuro.2004.15.4.267. Rev Neurosci. 2004. PMID: 15526551 Review.

10

Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice.

Brendza RP, Bacskai BJ, Cirrito JR, Simmons KA, Skoch JM, Klunk WE, Mathis CA, Bales KR, Paul SM, Hyman BT, Holtzman DM. Brendza RP, et al. Among authors: hyman bt. J Clin Invest. 2005 Feb;115(2):428-33. doi: 10.1172/JCI23269. J Clin Invest. 2005. PMID: 15668737 Free PMC article.

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