Culot M - Search Results

1

Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration.

Heymans M, Sevin E, Gosselet F, Lundquist S, Culot M. Heymans M, et al. Among authors: culot m. Eur J Pharm Biopharm. 2018 Jun;127:453-461. doi: 10.1016/j.ejpb.2018.03.007. Epub 2018 Mar 28. Eur J Pharm Biopharm. 2018. PMID: 29602020 Free article.

2

Modelling of the blood-brain barrier in drug discovery and development.

Cecchelli R, Berezowski V, Lundquist S, Culot M, Renftel M, Dehouck MP, Fenart L. Cecchelli R, et al. Among authors: culot m. Nat Rev Drug Discov. 2007 Aug;6(8):650-61. doi: 10.1038/nrd2368. Nat Rev Drug Discov. 2007. PMID: 17667956 Review.

3

An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening.

Culot M, Lundquist S, Vanuxeem D, Nion S, Landry C, Delplace Y, Dehouck MP, Berezowski V, Fenart L, Cecchelli R. Culot M, et al. Toxicol In Vitro. 2008 Apr;22(3):799-811. doi: 10.1016/j.tiv.2007.12.016. Epub 2008 Jan 8. Toxicol In Vitro. 2008. PMID: 18280105

4

Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study.

Culot M, Mysiorek C, Renftel M, Roussel BD, Hommet Y, Vivien D, Cecchelli R, Fenart L, Berezowski V, Dehouck MP, Lundquist S. Culot M, et al. Brain Res. 2009 Oct 19;1294:144-52. doi: 10.1016/j.brainres.2009.07.035. Epub 2009 Jul 23. Brain Res. 2009. PMID: 19631615

5

Brain pericytes from stress-susceptible pigs increase blood-brain barrier permeability in vitro.

Vandenhaute E, Culot M, Gosselet F, Dehouck L, Godfraind C, Franck M, Plouët J, Cecchelli R, Dehouck MP, Ruchoux MM. Vandenhaute E, et al. Among authors: culot m. Fluids Barriers CNS. 2012 Jun 29;9(1):11. doi: 10.1186/2045-8118-9-11. Fluids Barriers CNS. 2012. PMID: 22569151 Free PMC article.

6

In vitro blood-brain barrier model adapted to repeated-dose toxicological screening.

Fabulas-da Costa A, Aijjou R, Hachani J, Landry C, Cecchelli R, Culot M. Fabulas-da Costa A, et al. Among authors: culot m. Toxicol In Vitro. 2013 Sep;27(6):1944-53. doi: 10.1016/j.tiv.2013.06.026. Epub 2013 Jul 9. Toxicol In Vitro. 2013. PMID: 23850739

7

Accelerated Caco-2 cell permeability model for drug discovery.

Sevin E, Dehouck L, Fabulas-da Costa A, Cecchelli R, Dehouck MP, Lundquist S, Culot M. Sevin E, et al. Among authors: culot m. J Pharmacol Toxicol Methods. 2013 Nov-Dec;68(3):334-9. doi: 10.1016/j.vascn.2013.07.004. Epub 2013 Aug 3. J Pharmacol Toxicol Methods. 2013. PMID: 23916595

8

A simple method for assessing free brain/free plasma ratios using an in vitro model of the blood brain barrier.

Culot M, Fabulas-da Costa A, Sevin E, Szorath E, Martinsson S, Renftel M, Hongmei Y, Cecchelli R, Lundquist S. Culot M, et al. PLoS One. 2013 Dec 3;8(12):e80634. doi: 10.1371/journal.pone.0080634. eCollection 2013. PLoS One. 2013. PMID: 24312489 Free PMC article.

9

A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells.

Cecchelli R, Aday S, Sevin E, Almeida C, Culot M, Dehouck L, Coisne C, Engelhardt B, Dehouck MP, Ferreira L. Cecchelli R, et al. Among authors: culot m. PLoS One. 2014 Jun 17;9(6):e99733. doi: 10.1371/journal.pone.0099733. eCollection 2014. PLoS One. 2014. PMID: 24936790 Free PMC article.

10

Development and validation of a LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models.

Jähne EA, Eigenmann DE, Culot M, Cecchelli R, Walter FR, Deli MA, Tremmel R, Fricker G, Smiesko M, Hamburger M, Oufir M. Jähne EA, et al. Among authors: culot m. J Pharm Biomed Anal. 2014 Sep;98:235-46. doi: 10.1016/j.jpba.2014.05.026. Epub 2014 May 27. J Pharm Biomed Anal. 2014. PMID: 24949819

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