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FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation.
Gaschler MM, Andia AA, Liu H, Csuka JM, Hurlocker B, Vaiana CA, Heindel DW, Zuckerman DS, Bos PH, Reznik E, Ye LF, Tyurina YY, Lin AJ, Shchepinov MS, Chan AY, Peguero-Pereira E, Fomich MA, Daniels JD, Bekish AV, Shmanai VV, Kagan VE, Mahal LK, Woerpel KA, Stockwell BR. Gaschler MM, et al. Among authors: shchepinov ms. Nat Chem Biol. 2018 May;14(5):507-515. doi: 10.1038/s41589-018-0031-6. Epub 2018 Apr 2. Nat Chem Biol. 2018. PMID: 29610484 Free PMC article.
Characterization of a patient-derived variant of GPX4 for precision therapy.
Liu H, Forouhar F, Seibt T, Saneto R, Wigby K, Friedman J, Xia X, Shchepinov MS, Ramesh SK, Conrad M, Stockwell BR. Liu H, et al. Among authors: shchepinov ms. Nat Chem Biol. 2022 Jan;18(1):91-100. doi: 10.1038/s41589-021-00915-2. Epub 2021 Dec 20. Nat Chem Biol. 2022. PMID: 34931062 Free PMC article.
Deuterated polyunsaturated fatty acids inhibit photoirradiation-induced lipid peroxidation in lipid bilayers.
Firsov AM, Franco MSF, Chistyakov DV, Goriainov SV, Sergeeva MG, Kotova EA, Fomich MA, Bekish AV, Sharko OL, Shmanai VV, Itri R, Baptista MS, Antonenko YN, Shchepinov MS. Firsov AM, et al. Among authors: shchepinov ms. J Photochem Photobiol B. 2022 Apr;229:112425. doi: 10.1016/j.jphotobiol.2022.112425. Epub 2022 Mar 4. J Photochem Photobiol B. 2022. PMID: 35276579
Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation.
Hill S, Lamberson CR, Xu L, To R, Tsui HS, Shmanai VV, Bekish AV, Awad AM, Marbois BN, Cantor CR, Porter NA, Clarke CF, Shchepinov MS. Hill S, et al. Among authors: shchepinov ms. Free Radic Biol Med. 2012 Aug 15;53(4):893-906. doi: 10.1016/j.freeradbiomed.2012.06.004. Epub 2012 Jun 15. Free Radic Biol Med. 2012. PMID: 22705367 Free PMC article.
64 results