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Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation.
Vogl T, Stratis A, Wixler V, Völler T, Thurainayagam S, Jorch SK, Zenker S, Dreiling A, Chakraborty D, Fröhling M, Paruzel P, Wehmeyer C, Hermann S, Papantonopoulou O, Geyer C, Loser K, Schäfers M, Ludwig S, Stoll M, Leanderson T, Schultze JL, König S, Pap T, Roth J. Vogl T, et al. Among authors: roth j. J Clin Invest. 2018 May 1;128(5):1852-1866. doi: 10.1172/JCI89867. Epub 2018 Apr 3. J Clin Invest. 2018. PMID: 29611822 Free PMC article.
S100A9 interaction with TLR4 promotes tumor growth.
Källberg E, Vogl T, Liberg D, Olsson A, Björk P, Wikström P, Bergh A, Roth J, Ivars F, Leanderson T. Källberg E, et al. Among authors: roth j. PLoS One. 2012;7(3):e34207. doi: 10.1371/journal.pone.0034207. Epub 2012 Mar 28. PLoS One. 2012. PMID: 22470535 Free PMC article.
Doxycycline-induced expression of transgenic human tumor necrosis factor α in adult mice results in psoriasis-like arthritis.
Retser E, Schied T, Skryabin BV, Vogl T, Kanczler JM, Hamann N, Niehoff A, Hermann S, Eisenblätter M, Wachsmuth L, Pap T, van Lent PL, Loser K, Roth J, Zaucke F, Ludwig S, Wixler V. Retser E, et al. Among authors: roth j. Arthritis Rheum. 2013 Sep;65(9):2290-300. doi: 10.1002/art.38026. Arthritis Rheum. 2013. PMID: 23740547 Free PMC article.
Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8.
Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T. Fassl SK, et al. Among authors: roth j. J Immunol. 2015 Jan 15;194(2):575-83. doi: 10.4049/jimmunol.1401085. Epub 2014 Dec 10. J Immunol. 2015. PMID: 25505274 Clinical Trial.
Optical in vivo imaging of the alarmin S100A9 in tumor lesions allows for estimation of the individual malignant potential by evaluation of tumor-host cell interaction.
Becker A, Große Hokamp N, Zenker S, Flores-Borja F, Barzcyk K, Varga G, Roth J, Geyer C, Heindel W, Bremer C, Vogl T, Eisenblaetter M. Becker A, et al. Among authors: roth j. J Nucl Med. 2015 Mar;56(3):450-6. doi: 10.2967/jnumed.114.146688. Epub 2015 Feb 12. J Nucl Med. 2015. PMID: 25678492 Free article.
4,908 results