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A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma.
Labgaa I, Villacorta-Martin C, D'Avola D, Craig AJ, von Felden J, Martins-Filho SN, Sia D, Stueck A, Ward SC, Fiel MI, Mahajan M, Tabrizian P, Thung SN, Ang C, Friedman SL, Llovet JM, Schwartz M, Villanueva A. Labgaa I, et al. Among authors: friedman sl. Oncogene. 2018 Jul;37(27):3740-3752. doi: 10.1038/s41388-018-0206-3. Epub 2018 Apr 9. Oncogene. 2018. PMID: 29628508 Free PMC article.
E-cadherin is a novel transcriptional target of the KLF6 tumor suppressor.
DiFeo A, Narla G, Camacho-Vanegas O, Nishio H, Rose SL, Buller RE, Friedman SL, Walsh MJ, Martignetti JA. DiFeo A, et al. Among authors: friedman sl. Oncogene. 2006 Sep 28;25(44):6026-31. doi: 10.1038/sj.onc.1209611. Epub 2006 May 15. Oncogene. 2006. PMID: 16702959
A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.
Llovet JM, Chen Y, Wurmbach E, Roayaie S, Fiel MI, Schwartz M, Thung SN, Khitrov G, Zhang W, Villanueva A, Battiston C, Mazzaferro V, Bruix J, Waxman S, Friedman SL. Llovet JM, et al. Among authors: friedman sl. Gastroenterology. 2006 Dec;131(6):1758-67. doi: 10.1053/j.gastro.2006.09.014. Epub 2006 Sep 19. Gastroenterology. 2006. PMID: 17087938
Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation.
Kremer-Tal S, Narla G, Chen Y, Hod E, DiFeo A, Yea S, Lee JS, Schwartz M, Thung SN, Fiel IM, Banck M, Zimran E, Thorgeirsson SS, Mazzaferro V, Bruix J, Martignetti JA, Llovet JM, Friedman SL. Kremer-Tal S, et al. Among authors: friedman sl. J Hepatol. 2007 Apr;46(4):645-54. doi: 10.1016/j.jhep.2006.10.012. Epub 2006 Nov 27. J Hepatol. 2007. PMID: 17196295 Free PMC article.
Genomics and signaling pathways in hepatocellular carcinoma.
Villanueva A, Newell P, Chiang DY, Friedman SL, Llovet JM. Villanueva A, et al. Among authors: friedman sl. Semin Liver Dis. 2007 Feb;27(1):55-76. doi: 10.1055/s-2006-960171. Semin Liver Dis. 2007. PMID: 17295177 Review.
525 results