Wipf P - Search Results

1

XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent.

Polyzos AA, Wood NI, Williams P, Wipf P, Morton AJ, McMurray CT. Polyzos AA, et al. Among authors: wipf p. PLoS One. 2018 Apr 9;13(4):e0194580. doi: 10.1371/journal.pone.0194580. eCollection 2018. PLoS One. 2018. PMID: 29630611 Free PMC article.

2

Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease.

Xun Z, Rivera-Sánchez S, Ayala-Peña S, Lim J, Budworth H, Skoda EM, Robbins PD, Niedernhofer LJ, Wipf P, McMurray CT. Xun Z, et al. Among authors: wipf p. Cell Rep. 2012 Nov 29;2(5):1137-42. doi: 10.1016/j.celrep.2012.10.001. Epub 2012 Nov 1. Cell Rep. 2012. PMID: 23122961 Free PMC article.

3

Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes.

Polyzos A, Holt A, Brown C, Cosme C, Wipf P, Gomez-Marin A, Castro MR, Ayala-Peña S, McMurray CT. Polyzos A, et al. Among authors: wipf p. Hum Mol Genet. 2016 May 1;25(9):1792-802. doi: 10.1093/hmg/ddw051. Epub 2016 Feb 21. Hum Mol Genet. 2016. PMID: 26908614 Free PMC article.

4

Perfluorooctane Sulfonate (PFOS) Produces Dopaminergic Neuropathology in Caenorhabditis elegans.

Sammi SR, Foguth RM, Nieves CS, De Perre C, Wipf P, McMurray CT, Lee LS, Cannon JR. Sammi SR, et al. Among authors: wipf p. Toxicol Sci. 2019 Dec 1;172(2):417-434. doi: 10.1093/toxsci/kfz191. Toxicol Sci. 2019. PMID: 31428778 Free PMC article.

5

XJB-5-131 Is a Mild Uncoupler of Oxidative Phosphorylation.

Xun Z, Wipf P, McMurray CT. Xun Z, et al. Among authors: wipf p. J Huntingtons Dis. 2022;11(2):141-151. doi: 10.3233/JHD-220539. J Huntingtons Dis. 2022. PMID: 35404288 Free PMC article.

6

Pharmacological mitigation of tissue damage during brain microdialysis.

Nesbitt KM, Jaquins-Gerstl A, Skoda EM, Wipf P, Michael AC. Nesbitt KM, et al. Among authors: wipf p. Anal Chem. 2013 Sep 3;85(17):8173-9. doi: 10.1021/ac401201x. Epub 2013 Aug 20. Anal Chem. 2013. PMID: 23927692 Free PMC article.

7

New pyrazolopyrimidine inhibitors of protein kinase d as potent anticancer agents for prostate cancer cells.

Tandon M, Johnson J, Li Z, Xu S, Wipf P, Wang QJ. Tandon M, et al. Among authors: wipf p. PLoS One. 2013 Sep 23;8(9):e75601. doi: 10.1371/journal.pone.0075601. eCollection 2013. PLoS One. 2013. PMID: 24086585 Free PMC article.

8

SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest.

Tandon M, Salamoun JM, Carder EJ, Farber E, Xu S, Deng F, Tang H, Wipf P, Wang QJ. Tandon M, et al. Among authors: wipf p. PLoS One. 2015 Mar 6;10(3):e0119346. doi: 10.1371/journal.pone.0119346. eCollection 2015. PLoS One. 2015. PMID: 25747583 Free PMC article.

9

Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides.

Jiang J, Kurnikov I, Belikova NA, Xiao J, Zhao Q, Amoscato AA, Braslau R, Studer A, Fink MP, Greenberger JS, Wipf P, Kagan VE. Jiang J, et al. Among authors: wipf p. J Pharmacol Exp Ther. 2007 Mar;320(3):1050-60. doi: 10.1124/jpet.106.114769. Epub 2006 Dec 19. J Pharmacol Exp Ther. 2007. PMID: 17179468

10

A targeted library screen reveals a new inhibitor scaffold for protein kinase D.

Tandon M, Wang L, Xu Q, Xie X, Wipf P, Wang QJ. Tandon M, et al. Among authors: wipf p. PLoS One. 2012;7(9):e44653. doi: 10.1371/journal.pone.0044653. Epub 2012 Sep 18. PLoS One. 2012. PMID: 23028574 Free PMC article.

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