Ye L - Search Results

1

Mechanistic insights into allosteric regulation of the A_2A adenosine G protein-coupled receptor by physiological cations.

Ye L, Neale C, Sljoka A, Lyda B, Pichugin D, Tsuchimura N, Larda ST, Pomès R, García AE, Ernst OP, Sunahara RK, Prosser RS. Ye L, et al. Nat Commun. 2018 Apr 10;9(1):1372. doi: 10.1038/s41467-018-03314-9. Nat Commun. 2018. PMID: 29636462 Free PMC article.

2

A comparison of chemical shift sensitivity of trifluoromethyl tags: optimizing resolution in ¹⁹F NMR studies of proteins.

Ye L, Larda ST, Frank Li YF, Manglik A, Prosser RS. Ye L, et al. J Biomol NMR. 2015 May;62(1):97-103. doi: 10.1007/s10858-015-9922-y. Epub 2015 Mar 27. J Biomol NMR. 2015. PMID: 25813845 Free PMC article.

3

Activation of the A2A adenosine G-protein-coupled receptor by conformational selection.

Ye L, Van Eps N, Zimmer M, Ernst OP, Prosser RS. Ye L, et al. Nature. 2016 May 12;533(7602):265-8. doi: 10.1038/nature17668. Epub 2016 May 4. Nature. 2016. PMID: 27144352

4

The role of dimer asymmetry and protomer dynamics in enzyme catalysis.

Kim TH, Mehrabi P, Ren Z, Sljoka A, Ing C, Bezginov A, Ye L, Pomès R, Prosser RS, Pai EF. Kim TH, et al. Among authors: ye l. Science. 2017 Jan 20;355(6322):eaag2355. doi: 10.1126/science.aag2355. Science. 2017. PMID: 28104837

5

In Situ Reconstitution of the Adenosine A_2A Receptor in Spontaneously Formed Synthetic Liposomes.

Brea RJ, Cole CM, Lyda BR, Ye L, Prosser RS, Sunahara RK, Devaraj NK. Brea RJ, et al. Among authors: ye l. J Am Chem Soc. 2017 Mar 15;139(10):3607-3610. doi: 10.1021/jacs.6b12830. Epub 2017 Mar 6. J Am Chem Soc. 2017. PMID: 28263576 Free PMC article.

6

Activation processes in ligand-activated G protein-coupled receptors: A case study of the adenosine A_2A receptor.

Prosser RS, Ye L, Pandey A, Orazietti A. Prosser RS, et al. Among authors: ye l. Bioessays. 2017 Sep;39(9). doi: 10.1002/bies.201700072. Epub 2017 Aug 8. Bioessays. 2017. PMID: 28787091 Review.

7

Utilizing tagged paramagnetic shift reagents to monitor protein dynamics by NMR.

Ye L, Van Eps N, Li X, Ernst OP, Prosser RS. Ye L, et al. Biochim Biophys Acta Proteins Proteom. 2017 Nov;1865(11 Pt B):1555-1563. doi: 10.1016/j.bbapap.2017.09.011. Epub 2017 Sep 22. Biochim Biophys Acta Proteins Proteom. 2017. PMID: 28951313

8

High-Efficiency Expression of Yeast-Derived G-Protein Coupled Receptors and ¹⁹F Labeling for Dynamical Studies.

Ye L, Orazietti AP, Pandey A, Prosser RS. Ye L, et al. Methods Mol Biol. 2018;1688:407-421. doi: 10.1007/978-1-4939-7386-6_19. Methods Mol Biol. 2018. PMID: 29151220

9

Ligand modulation of the conformational dynamics of the A_2A adenosine receptor revealed by single-molecule fluorescence.

Fernandes DD, Neale C, Gomes GW, Li Y, Malik A, Pandey A, Orazietti AP, Wang X, Ye L, Scott Prosser R, Gradinaru CC. Fernandes DD, et al. Among authors: ye l. Sci Rep. 2021 Mar 15;11(1):5910. doi: 10.1038/s41598-021-84069-0. Sci Rep. 2021. PMID: 33723285 Free PMC article.

10

Intermediate-state-trapped mutants pinpoint G protein-coupled receptor conformational allostery.

Wang X, Neale C, Kim SK, Goddard WA, Ye L. Wang X, et al. Among authors: ye l. Nat Commun. 2023 Mar 10;14(1):1325. doi: 10.1038/s41467-023-36971-6. Nat Commun. 2023. PMID: 36899002 Free PMC article.

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