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Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells.
Powell J, Mota F, Steadman D, Soudy C, Miyauchi JT, Crosby S, Jarvis A, Reisinger T, Winfield N, Evans G, Finniear A, Yelland T, Chou YT, Chan AWE, O'Leary A, Cheng L, Liu D, Fotinou C, Milagre C, Martin JF, Jia H, Frankel P, Djordjevic S, Tsirka SE, Zachary IC, Selwood DL. Powell J, et al. J Med Chem. 2018 May 10;61(9):4135-4154. doi: 10.1021/acs.jmedchem.8b00210. Epub 2018 Apr 24. J Med Chem. 2018. PMID: 29648813 Free PMC article.
Architecture and hydration of the arginine-binding site of neuropilin-1.
Mota F, Fotinou C, Rana RR, Chan AWE, Yelland T, Arooz MT, O'Leary AP, Hutton J, Frankel P, Zachary I, Selwood D, Djordjevic S. Mota F, et al. FEBS J. 2018 Apr;285(7):1290-1304. doi: 10.1111/febs.14405. Epub 2018 Feb 25. FEBS J. 2018. PMID: 29430837 Free PMC article.
Molecular landscape of the overlap between Alzheimer's disease and somatic insulin-related diseases.
Ruisch IH, Widomska J, De Witte W, Mota NR, Fanelli G, Van Gils V, Jansen WJ, Vos SJB, Fóthi A, Barta C, Berkel S, Alam KA, Martinez A, Haavik J, O'Leary A, Slattery D, Sullivan M, Glennon J, Buitelaar JK, Bralten J, Franke B, Poelmans G. Ruisch IH, et al. Among authors: o leary a. Alzheimers Res Ther. 2024 Oct 28;16(1):239. doi: 10.1186/s13195-024-01609-2. Alzheimers Res Ther. 2024. PMID: 39465382 Free PMC article.
297 results