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Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers.
Popovici-Muller J, Lemieux RM, Artin E, Saunders JO, Salituro FG, Travins J, Cianchetta G, Cai Z, Zhou D, Cui D, Chen P, Straley K, Tobin E, Wang F, David MD, Penard-Lacronique V, Quivoron C, Saada V, de Botton S, Gross S, Dang L, Yang H, Utley L, Chen Y, Kim H, Jin S, Gu Z, Yao G, Luo Z, Lv X, Fang C, Yan L, Olaharski A, Silverman L, Biller S, Su SM, Yen K. Popovici-Muller J, et al. Among authors: gu z. ACS Med Chem Lett. 2018 Jan 19;9(4):300-305. doi: 10.1021/acsmedchemlett.7b00421. eCollection 2018 Apr 12. ACS Med Chem Lett. 2018. PMID: 29670690 Free PMC article.
AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency.
Kung C, Hixon J, Kosinski PA, Cianchetta G, Histen G, Chen Y, Hill C, Gross S, Si Y, Johnson K, DeLaBarre B, Luo Z, Gu Z, Yao G, Tang H, Fang C, Xu Y, Lv X, Biller S, Su SM, Yang H, Popovici-Muller J, Salituro F, Silverman L, Dang L. Kung C, et al. Among authors: gu z. Blood. 2017 Sep 14;130(11):1347-1356. doi: 10.1182/blood-2016-11-753525. Epub 2017 Jul 31. Blood. 2017. PMID: 28760888 Free PMC article.
Flexible Electrode Arrays Based on a Wide Bandgap Semiconductors for Chronic Implantable Multiplexed Sensing and Heart Pacemakers.
Truong TA, Huang X, Barton M, Ashok A, Al Abed A, Almasri R, Shivdasanic MN, Reshamwala R, Ingles J, Thai MT, Nguyen CC, Zhao S, Zhang X, Gu Z, Vasanth A, Peng S, Nguyen TK, Do N, Nguyen NT, Zhao H, Phan HP. Truong TA, et al. Among authors: gu z. ACS Nano. 2025 Jan 3. doi: 10.1021/acsnano.4c15294. Online ahead of print. ACS Nano. 2025. PMID: 39752298
The impact of common and rare genetic variants on bradyarrhythmia development.
Weng LC, Rämö JT, Jurgens SJ, Khurshid S, Chaffin M, Hall AW, Morrill VN, Wang X, Nauffal V, Sun YV, Beer D, Lee S, Nadkarni GN, Duong T, Wang B, Czuba T, Austin TR, Yoneda ZT, Friedman DJ, Clayton A, Hyman MC, Judy RL, Skanes AC, Orland KM, Treu TM, Oetjens MT, Alonso A, Soliman EZ, Lin H, Lunetta KL, van der Pals J, Issa TZ, Nafissi NA, May HT, Leong-Sit P, Roselli C, Choi SH; FinnGen; Million Veteran Program; Regeneron Genetics Center; Khan HR, Knight S, Karlsson Linnér R, Bezzina CR, Ripatti S, Heckbert SR, Gaziano JM, Loos RJF, Psaty BM, Smith JG, Benjamin EJ, Arking DE, Rader DJ, Shah SH, Roden DM, Damrauer SM, Eckhardt LL, Roberts JD, Cutler MJ, Shoemaker MB, Haggerty CM, Cho K, Palotie A, Wilson PWF, Ellinor PT, Lubitz SA. Weng LC, et al. Nat Genet. 2025 Jan 2. doi: 10.1038/s41588-024-01978-2. Online ahead of print. Nat Genet. 2025. PMID: 39747593
iMeta Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health.
Wang Y, Hou H, Luo H, Xun J, Ma C, Yang H, Bai D, Yousuf S, Lyu H, Zhang T, Wan X, Yao X, Ma T, Zhou Y, Zhu Z, Zeng M, An S, Bai Q, Bai Y, Cao G, Cao T, Cao Y, Chang C, Chang L, Chen B, Chen D, Chen D, Chen H, Chen J, Chen J, Chen WH, Chen X, Chen Y, Chen Z, Cheng C, Cheng Q, Dai XJ, Deng C, Deng F, Deng J, Dong CS, Dong L, Duan L, Duan Y, Fan Q, Fang C, Fang T, Fang W, Fang Z, Fu M, Fu M, Gao C, Gao H, Gao W, Gao X, Gao YZ, Geng Y, Gong W, Gu S, Gu X, Gu Z, Guo JW, Guo J, Guo Q, Guo X, Guo X, Han D, Han Z, Hao Y, He J, He J, He J, He R, Hou G, Hu B, Hu H, Hu Y, Hu Y, Hu Y, Huang G, Huang H, Huang J, Huang S, Jia B, Jian X, Jiang C, Jiang K, Jiang L, Jiang S, Jiao JY, Jin H, Jin J, Kong S, Lai X, Leng Y, Li B, Li B, Li F, Li H, Li H, Li J, Li K, Li L, Li L, Li M, Li P, Li W, Li W, Li X, Xuemeng L, Li Y, Li Y, Li Z, Liang L, Liang R, Liang Z, Liu Q, Liu D, Liu H, Liu J, Liu L, Liu L, Liu M, Liu R, Liu S, Liu T, Liu W, Liu W, Liu X, Liu Y, Liu Y, Liu Y, Liu Y, Liu Z, Liu Z, Liu Z, Long C, Long Y, Lu C, Lu C, Lu C, Lu Q, Luan Y, Luo P, Luo S, Ma N, Ma XY, Ma Y, Mao W, Meng Y, Ni Y, Ni Y, Ning K, Niu D, Peng K, Peng Z, Qian X, Qiu Z, Qu H, Qu Z, Ren Y, Ren Z, Shen Y, Shi L, Shi… See abstract for full author list ➔ Wang Y, et al. Among authors: gu z. Imeta. 2024 Dec 15;3(6):e251. doi: 10.1002/imt2.251. eCollection 2024 Dec. Imeta. 2024. PMID: 39742310 Free PMC article.
7,083 results