Silman I - Search Results

1

Potent 3-Hydroxy-2-Pyridine Aldoxime Reactivators of Organophosphate-Inhibited Cholinesterases with Predicted Blood-Brain Barrier Penetration.

Zorbaz T, Braïki A, Maraković N, Renou J, de la Mora E, Maček Hrvat N, Katalinić M, Silman I, Sussman JL, Mercey G, Gomez C, Mougeot R, Pérez B, Baati R, Nachon F, Weik M, Jean L, Kovarik Z, Renard PY. Zorbaz T, et al. Among authors: silman i. Chemistry. 2018 Jul 5;24(38):9675-9691. doi: 10.1002/chem.201801394. Epub 2018 Jun 8. Chemistry. 2018. PMID: 29672968

2

Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis.

Harel M, Sussman JL, Krejci E, Bon S, Chanal P, Massoulié J, Silman I. Harel M, et al. Among authors: silman i. Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):10827-31. doi: 10.1073/pnas.89.22.10827. Proc Natl Acad Sci U S A. 1992. PMID: 1438284 Free PMC article.

3

Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein.

Sussman JL, Harel M, Frolow F, Oefner C, Goldman A, Toker L, Silman I. Sussman JL, et al. Among authors: silman i. Science. 1991 Aug 23;253(5022):872-9. doi: 10.1126/science.1678899. Science. 1991. PMID: 1678899

4

Refined crystal structures of "aged" and "non-aged" organophosphoryl conjugates of gamma-chymotrypsin.

Harel M, Su CT, Frolow F, Ashani Y, Silman I, Sussman JL. Harel M, et al. Among authors: silman i. J Mol Biol. 1991 Oct 5;221(3):909-18. doi: 10.1016/0022-2836(91)80183-u. J Mol Biol. 1991. PMID: 1942036

5

Gamma-chymotrypsin is a complex of alpha-chymotrypsin with its own autolysis products.

Harel M, Su CT, Frolow F, Silman I, Sussman JL. Harel M, et al. Among authors: silman i. Biochemistry. 1991 May 28;30(21):5217-25. doi: 10.1021/bi00235a015. Biochemistry. 1991. PMID: 2036388

6

Purification and crystallization of a dimeric form of acetylcholinesterase from Torpedo californica subsequent to solubilization with phosphatidylinositol-specific phospholipase C.

Sussman JL, Harel M, Frolow F, Varon L, Toker L, Futerman AH, Silman I. Sussman JL, et al. Among authors: silman i. J Mol Biol. 1988 Oct 5;203(3):821-3. doi: 10.1016/0022-2836(88)90213-6. J Mol Biol. 1988. PMID: 2850366

7

Three-dimensional structures of acetylcholinesterase and of its complexes with anticholinesterase agents.

Silman I, Harel M, Axelsen P, Raves M, Sussman JL. Silman I, et al. Biochem Soc Trans. 1994 Aug;22(3):745-9. doi: 10.1042/bst0220745. Biochem Soc Trans. 1994. PMID: 7821677 Review. No abstract available.

8

A metastable state of Torpedo californica acetylcholinesterase generated by modification with organomercurials.

Kreimer DI, Dolginova EA, Raves M, Sussman JL, Silman I, Weiner L. Kreimer DI, et al. Among authors: silman i. Biochemistry. 1994 Dec 6;33(48):14407-18. doi: 10.1021/bi00252a006. Biochemistry. 1994. PMID: 7981200

9

Structure and dynamics of the active site gorge of acetylcholinesterase: synergistic use of molecular dynamics simulation and X-ray crystallography.

Axelsen PH, Harel M, Silman I, Sussman JL. Axelsen PH, et al. Among authors: silman i. Protein Sci. 1994 Feb;3(2):188-97. doi: 10.1002/pro.5560030204. Protein Sci. 1994. PMID: 8003956 Free PMC article.

10

Structure and functions of acetylcholinesterase and butyrylcholinesterase.

Massoulié J, Sussman J, Bon S, Silman I. Massoulié J, et al. Among authors: silman i. Prog Brain Res. 1993;98:139-46. doi: 10.1016/s0079-6123(08)62391-2. Prog Brain Res. 1993. PMID: 8248501 Review. No abstract available.

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