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499 results

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Page 1
Targeting GLP-1 receptor trafficking to improve agonist efficacy.
Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen BM, Scott R, Goldin R, Angkathunyakul N, Corrêa IR Jr, Bosco D, Johnson PR, Piemonti L, Marchetti P, Shapiro AMJ, Cochran BJ, Hanyaloglu AC, Inoue A, Tan T, Rutter GA, Tomas A, Bloom SR. Jones B, et al. Among authors: bosco d. Nat Commun. 2018 Apr 23;9(1):1602. doi: 10.1038/s41467-018-03941-2. Nat Commun. 2018. PMID: 29686402 Free PMC article.
Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.
Serre-Beinier V, Bosco D, Zulianello L, Charollais A, Caille D, Charpantier E, Gauthier BR, Diaferia GR, Giepmans BN, Lupi R, Marchetti P, Deng S, Buhler L, Berney T, Cirulli V, Meda P. Serre-Beinier V, et al. Among authors: bosco d. Hum Mol Genet. 2009 Feb 1;18(3):428-39. doi: 10.1093/hmg/ddn370. Epub 2008 Nov 10. Hum Mol Genet. 2009. PMID: 19000992 Free PMC article.
Lipotoxicity disrupts incretin-regulated human β cell connectivity.
Hodson DJ, Mitchell RK, Bellomo EA, Sun G, Vinet L, Meda P, Li D, Li WH, Bugliani M, Marchetti P, Bosco D, Piemonti L, Johnson P, Hughes SJ, Rutter GA. Hodson DJ, et al. Among authors: bosco d. J Clin Invest. 2013 Oct;123(10):4182-94. doi: 10.1172/JCI68459. Epub 2013 Sep 9. J Clin Invest. 2013. PMID: 24018562 Free PMC article.
ADCY5 couples glucose to insulin secretion in human islets.
Hodson DJ, Mitchell RK, Marselli L, Pullen TJ, Gimeno Brias S, Semplici F, Everett KL, Cooper DM, Bugliani M, Marchetti P, Lavallard V, Bosco D, Piemonti L, Johnson PR, Hughes SJ, Li D, Li WH, Shapiro AM, Rutter GA. Hodson DJ, et al. Among authors: bosco d. Diabetes. 2014 Sep;63(9):3009-21. doi: 10.2337/db13-1607. Epub 2014 Apr 16. Diabetes. 2014. PMID: 24740569 Free PMC article.
Incretin-modulated beta cell energetics in intact islets of Langerhans.
Hodson DJ, Tarasov AI, Gimeno Brias S, Mitchell RK, Johnston NR, Haghollahi S, Cane MC, Bugliani M, Marchetti P, Bosco D, Johnson PR, Hughes SJ, Rutter GA. Hodson DJ, et al. Among authors: bosco d. Mol Endocrinol. 2014 Jun;28(6):860-71. doi: 10.1210/me.2014-1038. Epub 2014 Apr 25. Mol Endocrinol. 2014. PMID: 24766140 Free PMC article.
Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells.
Gerber PA, Bellomo EA, Hodson DJ, Meur G, Solomou A, Mitchell RK, Hollinshead M, Chimienti F, Bosco D, Hughes SJ, Johnson PR, Rutter GA. Gerber PA, et al. Among authors: bosco d. Diabetologia. 2014 Aug;57(8):1635-44. doi: 10.1007/s00125-014-3266-0. Epub 2014 May 28. Diabetologia. 2014. PMID: 24865615 Free PMC article.
Calcineurin inhibitor-free immunosuppressive regimen in type 1 diabetes patients receiving islet transplantation: single-group phase 1/2 trial.
Maffi P, Berney T, Nano R, Niclauss N, Bosco D, Melzi R, Mercalli A, Magistretti P, De Cobelli F, Battaglia M, Scavini M, Demuylder-Mischler S, Secchi A, Piemonti L. Maffi P, et al. Among authors: bosco d. Transplantation. 2014 Dec 27;98(12):1301-9. doi: 10.1097/TP.0000000000000396. Transplantation. 2014. PMID: 25286053 Clinical Trial.
499 results