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Targeting GLP-1 receptor trafficking to improve agonist efficacy.
Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen BM, Scott R, Goldin R, Angkathunyakul N, Corrêa IR Jr, Bosco D, Johnson PR, Piemonti L, Marchetti P, Shapiro AMJ, Cochran BJ, Hanyaloglu AC, Inoue A, Tan T, Rutter GA, Tomas A, Bloom SR. Jones B, et al. Among authors: chabosseau p. Nat Commun. 2018 Apr 23;9(1):1602. doi: 10.1038/s41467-018-03941-2. Nat Commun. 2018. PMID: 29686402 Free PMC article.
A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells.
Buenaventura T, Kanda N, Douzenis PC, Jones B, Bloom SR, Chabosseau P, Corrêa IR Jr, Bosco D, Piemonti L, Marchetti P, Johnson PR, Shapiro AMJ, Rutter GA, Tomas A. Buenaventura T, et al. Among authors: chabosseau p. Diabetes. 2018 Mar;67(3):385-399. doi: 10.2337/db17-0639. Epub 2017 Dec 28. Diabetes. 2018. PMID: 29284659 Free article.
The α-cell in diabetes mellitus.
Gromada J, Chabosseau P, Rutter GA. Gromada J, et al. Among authors: chabosseau p. Nat Rev Endocrinol. 2018 Dec;14(12):694-704. doi: 10.1038/s41574-018-0097-y. Nat Rev Endocrinol. 2018. PMID: 30310153 Review.
Zinc and diabetes.
Chabosseau P, Rutter GA. Chabosseau P, et al. Arch Biochem Biophys. 2016 Dec 1;611:79-85. doi: 10.1016/j.abb.2016.05.022. Epub 2016 Jun 1. Arch Biochem Biophys. 2016. PMID: 27262257 Free article. Review.
Divergent effects of liraglutide, exendin-4, and sitagliptin on beta-cell mass and indicators of pancreatitis in a mouse model of hyperglycaemia.
Mondragon A, Davidsson D, Kyriakoudi S, Bertling A, Gomes-Faria R, Cohen P, Rothery S, Chabosseau P, Rutter GA, da Silva Xavier G. Mondragon A, et al. Among authors: chabosseau p. PLoS One. 2014 Aug 13;9(8):e104873. doi: 10.1371/journal.pone.0104873. eCollection 2014. PLoS One. 2014. PMID: 25119717 Free PMC article.
Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.
Mehta ZB, Fine N, Pullen TJ, Cane MC, Hu M, Chabosseau P, Meur G, Velayos-Baeza A, Monaco AP, Marselli L, Marchetti P, Rutter GA. Mehta ZB, et al. Among authors: chabosseau p. Am J Physiol Endocrinol Metab. 2016 Aug 1;311(2):E488-507. doi: 10.1152/ajpendo.00074.2016. Epub 2016 Jun 21. Am J Physiol Endocrinol Metab. 2016. PMID: 27329800 Free PMC article.
Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity.
Kleiner S, Gomez D, Megra B, Na E, Bhavsar R, Cavino K, Xin Y, Rojas J, Dominguez-Gutierrez G, Zambrowicz B, Carrat G, Chabosseau P, Hu M, Murphy AJ, Yancopoulos GD, Rutter GA, Gromada J. Kleiner S, et al. Among authors: chabosseau p. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):E7642-E7649. doi: 10.1073/pnas.1721418115. Epub 2018 Jul 23. Proc Natl Acad Sci U S A. 2018. PMID: 30038024 Free PMC article.
Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes.
de Jesus DS, Mak TCS, Wang YF, von Ohlen Y, Bai Y, Kane E, Chabosseau P, Chahrour CM, Distaso W, Salem V, Tomas A, Stoffel M, Rutter GA, Latreille M. de Jesus DS, et al. Among authors: chabosseau p. Mol Metab. 2021 Nov;53:101248. doi: 10.1016/j.molmet.2021.101248. Epub 2021 May 12. Mol Metab. 2021. PMID: 33989778 Free PMC article.
38 results