Wren JD - Search Results

1

Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.

Deepa SS, Pharaoh G, Kinter M, Diaz V, Fok WC, Riddle K, Pulliam D, Hill S, Fischer KE, Soto V, Georgescu C, Wren JD, Viscomi C, Richardson A, Van Remmen H. Deepa SS, et al. Among authors: wren jd. Aging Cell. 2018 Aug;17(4):e12769. doi: 10.1111/acel.12769. Epub 2018 Apr 25. Aging Cell. 2018. PMID: 29696791 Free PMC article.

2

Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.

Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H. Liu X, et al. Among authors: wren jd. Sci Signal. 2014 Oct 14;7(347):ra97. doi: 10.1126/scisignal.2005413. Sci Signal. 2014. PMID: 25314967 Free PMC article.

3

Trends in the production of scientific data analysis resources.

Hennessey J, Georgescu C, Wren JD. Hennessey J, et al. Among authors: wren jd. BMC Bioinformatics. 2014;15 Suppl 11(Suppl 11):S7. doi: 10.1186/1471-2105-15-S11-S7. Epub 2014 Oct 21. BMC Bioinformatics. 2014. PMID: 25350391 Free PMC article.

4

Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection.

Toth P, Tarantini S, Springo Z, Tucsek Z, Gautam T, Giles CB, Wren JD, Koller A, Sonntag WE, Csiszar A, Ungvari Z. Toth P, et al. Among authors: wren jd. Aging Cell. 2015 Jun;14(3):400-8. doi: 10.1111/acel.12315. Epub 2015 Feb 9. Aging Cell. 2015. PMID: 25677910 Free PMC article.

5

Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons.

Larabee CM, Georgescu C, Wren JD, Plafker SM. Larabee CM, et al. Among authors: wren jd. BMC Neurosci. 2015 Nov 13;16:76. doi: 10.1186/s12868-015-0194-y. BMC Neurosci. 2015. PMID: 26566974 Free PMC article.

6

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors.

Zhu Y, Tchkonia T, Fuhrmann-Stroissnigg H, Dai HM, Ling YY, Stout MB, Pirtskhalava T, Giorgadze N, Johnson KO, Giles CB, Wren JD, Niedernhofer LJ, Robbins PD, Kirkland JL. Zhu Y, et al. Among authors: wren jd. Aging Cell. 2016 Jun;15(3):428-35. doi: 10.1111/acel.12445. Epub 2016 Mar 18. Aging Cell. 2016. PMID: 26711051 Free PMC article.

7

Bisulfite oligonucleotide-capture sequencing for targeted base- and strand-specific absolute 5-methylcytosine quantitation.

Masser DR, Stanford DR, Hadad N, Giles CB, Wren JD, Sonntag WE, Richardson A, Freeman WM. Masser DR, et al. Among authors: wren jd. Age (Dordr). 2016 Jun;38(3):49. doi: 10.1007/s11357-016-9914-1. Epub 2016 Apr 18. Age (Dordr). 2016. PMID: 27091453 Free PMC article.

8

Myelin-specific Th17 cells induce severe relapsing optic neuritis with irreversible loss of retinal ganglion cells in C57BL/6 mice.

Larabee CM, Hu Y, Desai S, Georgescu C, Wren JD, Axtell RC, Plafker SM. Larabee CM, et al. Among authors: wren jd. Mol Vis. 2016 Apr 11;22:332-41. eCollection 2016. Mol Vis. 2016. PMID: 27122964 Free PMC article.

9

Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice.

Hadad N, Masser DR, Logan S, Wronowski B, Mangold CA, Clark N, Otalora L, Unnikrishnan A, Ford MM, Giles CB, Wren JD, Richardson A, Sonntag WE, Stanford DR, Freeman W. Hadad N, et al. Among authors: wren jd. Epigenetics Chromatin. 2016 Jul 13;9:30. doi: 10.1186/s13072-016-0080-6. eCollection 2016. Epigenetics Chromatin. 2016. PMID: 27413395 Free PMC article.

10

Effects of transgenic methionine sulfoxide reductase A (MsrA) expression on lifespan and age-dependent changes in metabolic function in mice.

Salmon AB, Kim G, Liu C, Wren JD, Georgescu C, Richardson A, Levine RL. Salmon AB, et al. Among authors: wren jd. Redox Biol. 2016 Dec;10:251-256. doi: 10.1016/j.redox.2016.10.012. Epub 2016 Oct 25. Redox Biol. 2016. PMID: 27821326 Free PMC article.

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