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Page 1
Structural insights on TRPV5 gating by endogenous modulators.
Hughes TET, Pumroy RA, Yazici AT, Kasimova MA, Fluck EC, Huynh KW, Samanta A, Molugu SK, Zhou ZH, Carnevale V, Rohacs T, Moiseenkova-Bell VY. Hughes TET, et al. Among authors: pumroy ra. Nat Commun. 2018 Oct 10;9(1):4198. doi: 10.1038/s41467-018-06753-6. Nat Commun. 2018. PMID: 30305626 Free PMC article.
Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2.
Fricke TC, Echtermeyer F, Zielke J, de la Roche J, Filipovic MR, Claverol S, Herzog C, Tominaga M, Pumroy RA, Moiseenkova-Bell VY, Zygmunt PM, Leffler A, Eberhardt MJ. Fricke TC, et al. Among authors: pumroy ra. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24359-24365. doi: 10.1073/pnas.1904332116. Epub 2019 Nov 12. Proc Natl Acad Sci U S A. 2019. PMID: 31719194 Free PMC article.
In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure-Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity.
Xu Z, Wise MC, Chokkalingam N, Walker S, Tello-Ruiz E, Elliott STC, Perales-Puchalt A, Xiao P, Zhu X, Pumroy RA, Fisher PD, Schultheis K, Schade E, Menis S, Guzman S, Andersen H, Broderick KE, Humeau LM, Muthumani K, Moiseenkova-Bell V, Schief WR, Weiner DB, Kulp DW. Xu Z, et al. Among authors: pumroy ra. Adv Sci (Weinh). 2020 Feb 27;7(8):1902802. doi: 10.1002/advs.201902802. eCollection 2020 Apr. Adv Sci (Weinh). 2020. PMID: 32328416 Free PMC article.
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.
Conde J, Pumroy RA, Baker C, Rodrigues T, Guerreiro A, Sousa BB, Marques MC, de Almeida BP, Lee S, Leites EP, Picard D, Samanta A, Vaz SH, Sieglitz F, Langini M, Remke M, Roque R, Weiss T, Weller M, Liu Y, Han S, Corzana F, Morais VA, Faria CC, Carvalho T, Filippakopoulos P, Snijder B, Barbosa-Morais NL, Moiseenkova-Bell VY, Bernardes GJL. Conde J, et al. Among authors: pumroy ra. ACS Cent Sci. 2021 May 26;7(5):868-881. doi: 10.1021/acscentsci.1c00070. Epub 2021 Apr 14. ACS Cent Sci. 2021. PMID: 34079902 Free PMC article.
Context-Specific Function of the Engineered Peptide Domain of PHP.B.
Martino RA, Fluck EC 3rd, Murphy J, Wang Q, Hoff H, Pumroy RA, Lee CY, Sims JJ, Roy S, Moiseenkova-Bell VY, Wilson JM. Martino RA, et al. Among authors: pumroy ra. J Virol. 2021 Sep 27;95(20):e0116421. doi: 10.1128/JVI.01164-21. Epub 2021 Aug 4. J Virol. 2021. PMID: 34346767 Free PMC article.
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