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Acetyl-CoA Carboxylase Inhibitor GS-0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients With Nonalcoholic Steatohepatitis.
Lawitz EJ, Coste A, Poordad F, Alkhouri N, Loo N, McColgan BJ, Tarrant JM, Nguyen T, Han L, Chung C, Ray AS, McHutchison JG, Subramanian GM, Myers RP, Middleton MS, Sirlin C, Loomba R, Nyangau E, Fitch M, Li K, Hellerstein M. Lawitz EJ, et al. Among authors: hellerstein m. Clin Gastroenterol Hepatol. 2018 Dec;16(12):1983-1991.e3. doi: 10.1016/j.cgh.2018.04.042. Epub 2018 Apr 26. Clin Gastroenterol Hepatol. 2018. PMID: 29705265
Isocaloric manipulation of macronutrients within a high-carbohydrate/moderate-fat diet induces unique effects on hepatic lipogenesis, steatosis and liver injury.
Pierce AA, Duwaerts CC, Soon RK, Siao K, Grenert JP, Fitch M, Hellerstein MK, Beysen C, Turner SM, Maher JJ. Pierce AA, et al. Among authors: hellerstein mk. J Nutr Biochem. 2016 Mar;29:12-20. doi: 10.1016/j.jnutbio.2015.10.020. Epub 2015 Nov 17. J Nutr Biochem. 2016. PMID: 26895660 Free PMC article.
Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood.
Decaris ML, Li KW, Emson CL, Gatmaitan M, Liu S, Wang Y, Nyangau E, Colangelo M, Angel TE, Beysen C, Cui J, Hernandez C, Lazaro L, Brenner DA, Turner SM, Hellerstein MK, Loomba R. Decaris ML, et al. Among authors: hellerstein mk. Hepatology. 2017 Jan;65(1):78-88. doi: 10.1002/hep.28860. Epub 2016 Nov 15. Hepatology. 2017. PMID: 27706836 Free PMC article.
325 results