Demerson CA - Search Results

1

Etodolac, a novel antiinflammatory agent. The syntheses and biological evaluation of its metabolites.

Humber LG, Ferdinandi E, Demerson CA, Ahmed S, Shah U, Mobilio D, Sabatucci J, De Lange B, Labbadia F, Hughes P. Humber LG, et al. Among authors: demerson ca. J Med Chem. 1988 Sep;31(9):1712-9. doi: 10.1021/jm00117a009. J Med Chem. 1988. PMID: 2970548

2

Etodolac (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid): a potent antiinflammatory drug. Conformation and absolute configuration of its active enantiomer.

Humber LG, Demerson CA, Swaminathan P, Bird PH. Humber LG, et al. Among authors: demerson ca. J Med Chem. 1986 May;29(5):871-4. doi: 10.1021/jm00155a047. J Med Chem. 1986. PMID: 2939246

3

Structure-activity relationships among analogues of pemedolac, cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]indo le-1-a cetic acid, a potent analgesic agent.

Mobilio D, Humber LG, Katz AH, Demerson CA, Hughes P, Brigance R, Conway K, Shah U, Williams G, Labbadia F, et al. Mobilio D, et al. Among authors: demerson ca. J Med Chem. 1988 Nov;31(11):2211-7. doi: 10.1021/jm00119a024. J Med Chem. 1988. PMID: 3263504

4

Synthesis and analgesic activity of pemedolac (cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]ind ole-1- acetic acid).

Katz AH, Demerson CA, Shaw CC, Asselin AA, Humber LG, Conway KM, Gavin G, Guinosso C, Jensen NP, Mobilio D, et al. Katz AH, et al. Among authors: demerson ca. J Med Chem. 1988 Jun;31(6):1244-50. doi: 10.1021/jm00401a029. J Med Chem. 1988. PMID: 3373493

5

Resolution of etodolac and antiinflammatory and prostaglandin synthetase inhibiting properties of the enantiomers.

Demerson CA, Humber LG, Abraham NA, Schilling G, Martel RR, Pace-Asciak C. Demerson CA, et al. J Med Chem. 1983 Dec;26(12):1778-80. doi: 10.1021/jm00366a025. J Med Chem. 1983. PMID: 6227748

6

Chemistry and antiinflammatory activities of prodolic-acid and related 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-alkanoic acids. 1.

Demerson CA, Humber LG, Dobson TA, Martel RR. Demerson CA, et al. J Med Chem. 1975 Feb;18(2):189-91. doi: 10.1021/jm00236a017. J Med Chem. 1975. PMID: 1120985

7

Etodolic acid and related compounds. Chemistry and antiinflammatory actions of some potent di- and trisubstituted 1, 3, 4, 9-tetrahydropyrano[3, 4-b]indole-1-acetic acids.

Martel RR, Demerson CA, Humber LG, Philipp AH. Martel RR, et al. Among authors: demerson ca. J Med Chem. 1976 Mar;19(3):391-5. doi: 10.1021/jm00225a010. J Med Chem. 1976. PMID: 1255663

8

3,4-Dihydro-1H-1,4-oxazino[4,3-a]indoles as potential antidepressants.

Demerson CA, Santroch G, Humber LG. Demerson CA, et al. J Med Chem. 1975 Jun;18(6):577-80. doi: 10.1021/jm00240a010. J Med Chem. 1975. PMID: 1151971

9

Conversion of a cyclooxygenase (CO) inhibitor into a 5-lipoxygenase (LO) inhibitor: a general route to novel orally active anti-inflammatory and anti-allergy drugs.

Kreft AF, Failli AA, Musser JH, Kubrak DM, Banker AL, Steffan R, Demerson CA, Nelson JA, Shah US, Gray W, et al. Kreft AF, et al. Among authors: demerson ca. Drugs Exp Clin Res. 1991;17(8):381-7. Drugs Exp Clin Res. 1991. PMID: 1822830

10

Pyrrolo(4,3,2-de)isoquinolines with central nervous system and antihypertensive activities.

Demerson CA, Philipp AH, Humber LG, Kraml MJ, Charest MP, Tom H, Vávra I. Demerson CA, et al. J Med Chem. 1974 Nov;17(11):1140-5. doi: 10.1021/jm00257a003. J Med Chem. 1974. PMID: 4415412 No abstract available.

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