Kostenis E - Search Results

1

Repurposing HAMI3379 to Block GPR17 and Promote Rodent and Human Oligodendrocyte Differentiation.

Merten N, Fischer J, Simon K, Zhang L, Schröder R, Peters L, Letombe AG, Hennen S, Schrage R, Bödefeld T, Vermeiren C, Gillard M, Mohr K, Lu QR, Brüstle O, Gomeza J, Kostenis E. Merten N, et al. Among authors: kostenis e. Cell Chem Biol. 2018 Jun 21;25(6):775-786.e5. doi: 10.1016/j.chembiol.2018.03.012. Epub 2018 Apr 26. Cell Chem Biol. 2018. PMID: 29706593 Free PMC article.

2

Potentiation by alcuronium of the antimuscarinic effect of N-methylscopolamine in guinea pig left atria.

Maass A, Kostenis E, Mohr K. Maass A, et al. Among authors: kostenis e. Eur J Pharmacol. 1995 Jan 5;272(1):103-6. doi: 10.1016/0014-2999(94)00664-s. Eur J Pharmacol. 1995. PMID: 7713140

3

[Omeprazole].

Kostenis E, Mohr K. Kostenis E, et al. Dtsch Med Wochenschr. 1994 Aug 26;119(34-35):1173-4. doi: 10.1055/s-0029-1235090. Dtsch Med Wochenschr. 1994. PMID: 8076506 German. No abstract available.

4

Search for the pharmacophore of bispyridinium-type allosteric modulators of muscarinic receptors.

Botero Cid MH, Holzgrabe U, Kostenis E, Mohr K, Tränkle C. Botero Cid MH, et al. Among authors: kostenis e. J Med Chem. 1994 May 13;37(10):1439-45. doi: 10.1021/jm00036a008. J Med Chem. 1994. PMID: 8182702

5

Two-point kinetic experiments to quantify allosteric effects on radioligand dissociation.

Kostenis E, Mohr K. Kostenis E, et al. Trends Pharmacol Sci. 1996 Aug;17(8):280-3. doi: 10.1016/0165-6147(96)10034-1. Trends Pharmacol Sci. 1996. PMID: 8810873 Review.

6

Search for lead structures to develop new allosteric modulators of muscarinic receptors.

Tränkle C, Kostenis E, Burgmer U, Mohr K. Tränkle C, et al. Among authors: kostenis e. J Pharmacol Exp Ther. 1996 Nov;279(2):926-33. J Pharmacol Exp Ther. 1996. PMID: 8930201

7

Evidence for a multiple binding mode of bispyridinium-type allosteric modulators of muscarinic receptors.

Kostenis E, Botero Cid HM, Holzgrabe Y, Mohr K. Kostenis E, et al. Eur J Pharmacol. 1996 Oct 31;314(3):385-92. doi: 10.1016/s0014-2999(96)00568-7. Eur J Pharmacol. 1996. PMID: 8957263

8

Bisquaternary ligands of the common allosteric site of M2 acetylcholine receptors: search for the minimum essential distances between the pharmacophoric elements.

Nassif-Makki T, Tränkle C, Zlotos D, Bejeuhr G, Cambareri A, Pfletschinger C, Kostenis E, Mohr K, Holzgrabe U. Nassif-Makki T, et al. Among authors: kostenis e. J Med Chem. 1999 Mar 11;42(5):849-58. doi: 10.1021/jm981023f. J Med Chem. 1999. PMID: 10072682

9

Structure-activity relationships in a series of bisquaternary bisphthalimidine derivatives modulating the muscarinic M(2)-receptor allosterically.

Botero Cid HM, Tränkle C, Baumann K, Pick R, Mies-Klomfass E, Kostenis E, Mohr K, Holzgrabe U. Botero Cid HM, et al. Among authors: kostenis e. J Med Chem. 2000 Jun 1;43(11):2155-64. doi: 10.1021/jm991136e. J Med Chem. 2000. PMID: 10841794

10

Muscarinic allosteric modulation: M2/M3 subtype selectivity of gallamine is independent of G-protein coupling specificity.

Tränkle C, Kostenis E, Mohr K. Tränkle C, et al. Among authors: kostenis e. Naunyn Schmiedebergs Arch Pharmacol. 2001 Aug;364(2):172-8. doi: 10.1007/s002100100441. Naunyn Schmiedebergs Arch Pharmacol. 2001. PMID: 11534857

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