Vasella AT - Search Results

1

Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases.

Heightman TD, Vasella AT. Heightman TD, et al. Among authors: vasella at. Angew Chem Int Ed Engl. 1999 Mar 15;38(6):750-770. doi: 10.1002/(SICI)1521-3773(19990315)38:6<750::AID-ANIE750>3.0.CO;2-6. Angew Chem Int Ed Engl. 1999. PMID: 29711789 Review.

2

A structural view of the action of Escherichia coli (lacZ) beta-galactosidase.

Juers DH, Heightman TD, Vasella A, McCarter JD, Mackenzie L, Withers SG, Matthews BW. Juers DH, et al. Biochemistry. 2001 Dec 11;40(49):14781-94. doi: 10.1021/bi011727i. Biochemistry. 2001. PMID: 11732897

3

Carbocyclic Analogues of N-Acetyl-2,3-didehydro-2-deoxy-D-neuraminic Acid (Neu5Ac2en, DANA): Synthesis and Inhibition of Viral and Bacterial Neuraminidases.

Vorwerk S, Vasella A. Vorwerk S, et al. Angew Chem Int Ed Engl. 1998 Jul 3;37(12):1732-1734. doi: 10.1002/(SICI)1521-3773(19980703)37:12<1732::AID-ANIE1732>3.0.CO;2-I. Angew Chem Int Ed Engl. 1998. PMID: 29711519

4

Glycosidase mechanisms.

Vasella A, Davies GJ, Böhm M. Vasella A, et al. Curr Opin Chem Biol. 2002 Oct;6(5):619-29. doi: 10.1016/s1367-5931(02)00380-0. Curr Opin Chem Biol. 2002. PMID: 12413546 Review.

5

Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc-imidazole hybrid inhibitor.

Shanmugasundaram B, Debowski AW, Dennis RJ, Davies GJ, Vocadlo DJ, Vasella A. Shanmugasundaram B, et al. Chem Commun (Camb). 2006 Nov 13;(42):4372-4. doi: 10.1039/b612154c. Epub 2006 Sep 29. Chem Commun (Camb). 2006. PMID: 17057847

6

Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.

Mitchell EP, Withers SG, Ermert P, Vasella AT, Garman EF, Oikonomakos NG, Johnson LN. Mitchell EP, et al. Among authors: vasella at. Biochemistry. 1996 Jun 11;35(23):7341-55. doi: 10.1021/bi960072w. Biochemistry. 1996. PMID: 8652510

7

The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.

Caines ME, Hancock SM, Tarling CA, Wrodnigg TM, Stick RV, Stütz AE, Vasella A, Withers SG, Strynadka NC. Caines ME, et al. Angew Chem Int Ed Engl. 2007;46(24):4474-6. doi: 10.1002/anie.200700268. Angew Chem Int Ed Engl. 2007. PMID: 17487923 No abstract available.

8

Channels at the catalytic site of glycogen phosphorylase b: binding and kinetic studies with the beta-glycosidase inhibitor D-gluconohydroximo-1,5-lactone N-phenylurethane.

Barford D, Schwabe JW, Oikonomakos NG, Acharya KR, Hajdu J, Papageorgiou AC, Martin JL, Knott JC, Vasella A, Johnson LN. Barford D, et al. Biochemistry. 1988 Sep 6;27(18):6733-41. doi: 10.1021/bi00418a014. Biochemistry. 1988. PMID: 3143403

9

Structural rationale for low-nanomolar binding of transition state mimics to a family GH3 beta-D-glucan glucohydrolase from barley.

Hrmova M, Streltsov VA, Smith BJ, Vasella A, Varghese JN, Fincher GB. Hrmova M, et al. Biochemistry. 2005 Dec 20;44(50):16529-39. doi: 10.1021/bi0514818. Biochemistry. 2005. PMID: 16342944

10

Influence of 4'-O-Glycoside Constitution and Configuration on Ribosomal Selectivity of Paromomycin.

Matsushita T, Chen W, Juskeviciene R, Teo Y, Shcherbakov D, Vasella A, Böttger EC, Crich D. Matsushita T, et al. J Am Chem Soc. 2015 Jun 24;137(24):7706-17. doi: 10.1021/jacs.5b02248. Epub 2015 Jun 12. J Am Chem Soc. 2015. PMID: 26024064

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