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Page 1
Epitope Mapping Using Yeast Display and Next Generation Sequencing.
Van Blarcom T, Rossi A, Foletti D, Sundar P, Pitts S, Melton Z, Telman D, Zhao L, Cheung WL, Berka J, Zhai W, Strop P, Pons J, Rajpal A, Chaparro-Riggers J. Van Blarcom T, et al. Among authors: pons j. Methods Mol Biol. 2018;1785:89-118. doi: 10.1007/978-1-4939-7841-0_7. Methods Mol Biol. 2018. PMID: 29714014
Precise and efficient antibody epitope determination through library design, yeast display and next-generation sequencing.
Van Blarcom T, Rossi A, Foletti D, Sundar P, Pitts S, Bee C, Melton Witt J, Melton Z, Hasa-Moreno A, Shaughnessy L, Telman D, Zhao L, Cheung WL, Berka J, Zhai W, Strop P, Chaparro-Riggers J, Shelton DL, Pons J, Rajpal A. Van Blarcom T, et al. Among authors: pons j. J Mol Biol. 2015 Mar 27;427(6 Pt B):1513-1534. doi: 10.1016/j.jmb.2014.09.020. Epub 2014 Oct 2. J Mol Biol. 2015. PMID: 25284753
Synthetic antibodies designed on natural sequence landscapes.
Zhai W, Glanville J, Fuhrmann M, Mei L, Ni I, Sundar PD, Van Blarcom T, Abdiche Y, Lindquist K, Strohner R, Telman D, Cappuccilli G, Finlay WJ, Van den Brulle J, Cox DR, Pons J, Rajpal A. Zhai W, et al. Among authors: pons j. J Mol Biol. 2011 Sep 9;412(1):55-71. doi: 10.1016/j.jmb.2011.07.018. Epub 2011 Jul 23. J Mol Biol. 2011. PMID: 21787786
Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair.
Strop P, Ho WH, Boustany LM, Abdiche YN, Lindquist KC, Farias SE, Rickert M, Appah CT, Pascua E, Radcliffe T, Sutton J, Chaparro-Riggers J, Chen W, Casas MG, Chin SM, Wong OK, Liu SH, Vergara G, Shelton D, Rajpal A, Pons J. Strop P, et al. Among authors: pons j. J Mol Biol. 2012 Jul 13;420(3):204-19. doi: 10.1016/j.jmb.2012.04.020. Epub 2012 Apr 25. J Mol Biol. 2012. PMID: 22543237
High-throughput epitope binning assays on label-free array-based biosensors can yield exquisite epitope discrimination that facilitates the selection of monoclonal antibodies with functional activity.
Abdiche YN, Miles A, Eckman J, Foletti D, Van Blarcom TJ, Yeung YA, Pons J, Rajpal A. Abdiche YN, et al. Among authors: pons j. PLoS One. 2014 Mar 20;9(3):e92451. doi: 10.1371/journal.pone.0092451. eCollection 2014. PLoS One. 2014. PMID: 24651868 Free PMC article.
Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire.
Yeung YA, Foletti D, Deng X, Abdiche Y, Strop P, Glanville J, Pitts S, Lindquist K, Sundar PD, Sirota M, Hasa-Moreno A, Pham A, Melton Witt J, Ni I, Pons J, Shelton D, Rajpal A, Chaparro-Riggers J. Yeung YA, et al. Among authors: pons j. Nat Commun. 2016 Nov 18;7:13376. doi: 10.1038/ncomms13376. Nat Commun. 2016. PMID: 27857134 Free PMC article.
Productive common light chain libraries yield diverse panels of high affinity bispecific antibodies.
Van Blarcom T, Lindquist K, Melton Z, Cheung WL, Wagstrom C, McDonough D, Valle Oseguera C, Ding S, Rossi A, Potluri S, Sundar P, Pitts S, Sirota M, Galindo Casas M, Yan Y, Jones J, Roe-Zurz Z, Srivatsa Srinivasan S, Zhai W, Pons J, Rajpal A, Chaparro-Riggers J. Van Blarcom T, et al. Among authors: pons j. MAbs. 2018 Feb/Mar;10(2):256-268. doi: 10.1080/19420862.2017.1406570. Epub 2017 Dec 14. MAbs. 2018. PMID: 29227213 Free PMC article.
Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire.
Glanville J, Zhai W, Berka J, Telman D, Huerta G, Mehta GR, Ni I, Mei L, Sundar PD, Day GM, Cox D, Rajpal A, Pons J. Glanville J, et al. Among authors: pons j. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20216-21. doi: 10.1073/pnas.0909775106. Epub 2009 Oct 29. Proc Natl Acad Sci U S A. 2009. PMID: 19875695 Free PMC article.
1,132 results