Yi H - Search Results

1

A novel small molecule inhibitor of MDM2-p53 (APG-115) enhances radiosensitivity of gastric adenocarcinoma.

Yi H, Yan X, Luo Q, Yuan L, Li B, Pan W, Zhang L, Chen H, Wang J, Zhang Y, Zhai Y, Qiu MZ, Yang DJ. Yi H, et al. J Exp Clin Cancer Res. 2018 May 2;37(1):97. doi: 10.1186/s13046-018-0765-8. J Exp Clin Cancer Res. 2018. PMID: 29716622 Free PMC article.

2

Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells.

Chen H, Luo D, Zhang L, Lin X, Luo Q, Yi H, Wang J, Yan X, Li B, Chen Y, Liu X, Zhang H, Liu S, Qiu M, Yang D, Jiang N. Chen H, et al. Among authors: yi h. Oncotarget. 2017 Jun 27;8(26):43008-43022. doi: 10.18632/oncotarget.17398. Oncotarget. 2017. PMID: 28498808 Free PMC article.

3

APG-1252-12A induces mitochondria-dependent apoptosis through inhibiting the antiapoptotic proteins Bcl-2/Bcl-xl in HL-60 cells.

Wang J, Yang D, Luo Q, Qiu M, Zhang L, Li B, Chen H, Yi H, Yan X, Li S, Sun J. Wang J, et al. Among authors: yi h. Int J Oncol. 2017 Aug;51(2):563-572. doi: 10.3892/ijo.2017.4028. Epub 2017 Jun 6. Int J Oncol. 2017. PMID: 28586007

4

Novel smac mimetic APG-1387 elicits ovarian cancer cell killing through TNF-alpha, Ripoptosome and autophagy mediated cell death pathway.

Li BX, Wang HB, Qiu MZ, Luo QY, Yi HJ, Yan XL, Pan WT, Yuan LP, Zhang YX, Xu JH, Zhang L, Yang DJ. Li BX, et al. J Exp Clin Cancer Res. 2018 Mar 12;37(1):53. doi: 10.1186/s13046-018-0703-9. J Exp Clin Cancer Res. 2018. PMID: 29530056 Free PMC article.

5

A novel SMAC mimetic APG-1387 exhibits dual antitumor effect on HBV-positive hepatocellular carcinoma with high expression of cIAP2 by inducing apoptosis and enhancing innate anti-tumor immunity.

Pan W, Luo Q, Yan X, Yuan L, Yi H, Zhang L, Li B, Zhang Y, Sun J, Qiu MZ, Yang DJ. Pan W, et al. Among authors: yi h. Biochem Pharmacol. 2018 Aug;154:127-135. doi: 10.1016/j.bcp.2018.04.020. Epub 2018 Apr 18. Biochem Pharmacol. 2018. PMID: 29679556

6

Correction to: Novel smac mimetic APG-1387 elicits ovarian cancer cell killing through TNF-alpha, Ripoptosome and autophagy mediated cell death pathway.

Li BX, Wang HB, Qiu MZ, Luo QY, Yi HJ, Yan XL, Pan WT, Yuan LP, Zhang YX, Xu JH, Zhang L, Yang DJ. Li BX, et al. J Exp Clin Cancer Res. 2018 May 24;37(1):108. doi: 10.1186/s13046-018-0774-7. J Exp Clin Cancer Res. 2018. PMID: 29793514 Free PMC article.

7

A Novel BCL-2 Inhibitor APG-2575 Exerts Synthetic Lethality With BTK or MDM2-p53 Inhibitor in Diffuse Large B-Cell Lymphoma.

Luo Q, Pan W, Zhou S, Wang G, Yi H, Zhang L, Yan X, Yuan L, Liu Z, Wang J, Chen H, Qiu M, Yang D, Sun J. Luo Q, et al. Among authors: yi h. Oncol Res. 2020 Sep 1;28(4):331-344. doi: 10.3727/096504020X15825405463920. Epub 2020 Feb 24. Oncol Res. 2020. PMID: 32093809 Free PMC article.

8

Bcl-2/Bcl-xl inhibitor APG-1252-M1 is a promising therapeutic strategy for gastric carcinoma.

Yi H, Qiu MZ, Yuan L, Luo Q, Pan W, Zhou S, Zhang L, Yan X, Yang DJ. Yi H, et al. Cancer Med. 2020 Jun;9(12):4197-4206. doi: 10.1002/cam4.3090. Epub 2020 Apr 28. Cancer Med. 2020. PMID: 32346976 Free PMC article.

9

Prognostic impact of the combination of HIF‑1α and GLUT1 in patients with oesophageal squamous cell carcinoma.

Yi H, Han Y, Li Q, Lin R, Zhang J, Yang Y, Wang X, Zhang L. Yi H, et al. Oncol Lett. 2023 Jul 31;26(3):404. doi: 10.3892/ol.2023.13990. eCollection 2023 Sep. Oncol Lett. 2023. PMID: 37600334 Free PMC article.

10

Synergistic effects of Smac mimetic APG-1387 with anti-PD-1 antibody are attributed to increased CD3 + NK1.1 + cell recruitment secondary to induction of cytokines from tumor cells.

Pan W, Luo Q, Liang E, Shi M, Sun J, Shen H, Lu Z, Zhang L, Yan X, Yuan L, Zhou S, Yi H, Zhai Y, Qiu MZ, Yang D. Pan W, et al. Among authors: yi h. Cancer Cell Int. 2024 May 24;24(1):181. doi: 10.1186/s12935-024-03373-7. Cancer Cell Int. 2024. PMID: 38790057 Free PMC article.

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