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PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein.
Daniel PM, Filiz G, Brown DV, Christie M, Waring PM, Zhang Y, Haynes JM, Pouton C, Flanagan D, Vincan E, Johns TG, Montgomery K, Phillips WA, Mantamadiotis T. Daniel PM, et al. Among authors: haynes jm. Neuro Oncol. 2018 Sep 3;20(10):1344-1355. doi: 10.1093/neuonc/noy068. Neuro Oncol. 2018. PMID: 29718345 Free PMC article.
Pharmaceutical applications of embryonic stem cells.
Pouton CW, Haynes JM. Pouton CW, et al. Among authors: haynes jm. Adv Drug Deliv Rev. 2005 Dec 12;57(13):1918-34. doi: 10.1016/j.addr.2005.08.003. Epub 2005 Nov 9. Adv Drug Deliv Rev. 2005. PMID: 16290153 Review.
A novel highly selective adenosine A1 receptor agonist VCP28 reduces ischemia injury in a cardiac cell line and ischemia-reperfusion injury in isolated rat hearts at concentrations that do not affect heart rate.
Urmaliya VB, Pouton CW, Devine SM, Haynes JM, Warfe L, Scammells PJ, White PJ. Urmaliya VB, et al. Among authors: haynes jm. J Cardiovasc Pharmacol. 2010 Sep;56(3):282-92. doi: 10.1097/FJC.0b013e3181eb8563. J Cardiovasc Pharmacol. 2010. PMID: 20571427
A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives.
Goulburn AL, Alden D, Davis RP, Micallef SJ, Ng ES, Yu QC, Lim SM, Soh CL, Elliott DA, Hatzistavrou T, Bourke J, Watmuff B, Lang RJ, Haynes JM, Pouton CW, Giudice A, Trounson AO, Anderson SA, Stanley EG, Elefanty AG. Goulburn AL, et al. Among authors: haynes jm. Stem Cells. 2011 Mar;29(3):462-73. doi: 10.1002/stem.587. Stem Cells. 2011. PMID: 21425409
171 results