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Aberrant nuclear localization and gene mutation of beta-catenin in low-grade adenocarcinoma of fetal lung type: up-regulation of the Wnt signaling pathway may be a common denominator for the development of tumors that form morules.
Nakatani Y, Masudo K, Miyagi Y, Inayama Y, Kawano N, Tanaka Y, Kato K, Ito T, Kitamura H, Nagashima Y, Yamanaka S, Nakamura N, Sano J, Ogawa N, Ishiwa N, Notohara K, Resl M, Mark EJ. Nakatani Y, et al. Among authors: ito t. Mod Pathol. 2002 Jun;15(6):617-24. doi: 10.1038/modpathol.3880575. Mod Pathol. 2002. PMID: 12065775
Biotin-rich, optically clear nuclei express estrogen receptor-beta: tumors with morules may develop under the influence of estrogen and aberrant beta-catenin expression.
Nakatani Y, Masudo K, Nozawa A, Inayama Y, Yamanaka S, Ito T, Kitamura H, Notohara K, Kashima K, Yokoyama S, Tsujimoto M, Tamai S, Abe Y, Resl M, Mark EJ. Nakatani Y, et al. Among authors: ito t. Hum Pathol. 2004 Jul;35(7):869-74. doi: 10.1016/j.humpath.2004.03.018. Hum Pathol. 2004. PMID: 15257551
K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.
Okudela K, Hayashi H, Ito T, Yazawa T, Suzuki T, Nakane Y, Sato H, Ishi H, KeQin X, Masuda A, Takahashi T, Kitamura H. Okudela K, et al. Among authors: ito t. Am J Pathol. 2004 Jan;164(1):91-100. doi: 10.1016/S0002-9440(10)63100-8. Am J Pathol. 2004. PMID: 14695323 Free PMC article.
Insulinoma-associated protein 1 (INSM1) is a useful marker for pancreatic neuroendocrine tumor.
Tanigawa M, Nakayama M, Taira T, Hattori S, Mihara Y, Kondo R, Kusano H, Nakamura K, Abe Y, Ishida Y, Okabe Y, Hisaka T, Okuda K, Fujino K, Ito T, Kawahara A, Naito Y, Yamaguchi R, Akiba J, Akagi Y, Yano H. Tanigawa M, et al. Among authors: ito t. Med Mol Morphol. 2018 Mar;51(1):32-40. doi: 10.1007/s00795-017-0167-6. Epub 2017 Aug 28. Med Mol Morphol. 2018. PMID: 28849340
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