Rennie PS - Search Results

1

Cheminformatics Driven Development of Novel Therapies for Drug Resistant Prostate Cancer.

Ban F, Dalal K, LeBlanc E, Morin H, Rennie PS, Cherkasov A. Ban F, et al. Among authors: rennie ps. Mol Inform. 2018 Sep;37(9-10):e1800043. doi: 10.1002/minf.201800043. Epub 2018 May 7. Mol Inform. 2018. PMID: 29733509 Review.

2

Identification of novel androgen receptor antagonists using structure- and ligand-based methods.

Li H, Ren X, Leblanc E, Frewin K, Rennie PS, Cherkasov A. Li H, et al. Among authors: rennie ps. J Chem Inf Model. 2013 Jan 28;53(1):123-30. doi: 10.1021/ci300514v. Epub 2013 Jan 16. J Chem Inf Model. 2013. PMID: 23278403

3

Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer.

Lallous N, Dalal K, Cherkasov A, Rennie PS. Lallous N, et al. Among authors: rennie ps. Int J Mol Sci. 2013 Jun 14;14(6):12496-519. doi: 10.3390/ijms140612496. Int J Mol Sci. 2013. PMID: 23771019 Free PMC article. Review.

4

Discovery of 1H-indole-2-carboxamides as novel inhibitors of the androgen receptor binding function 3 (BF3).

Ban F, Leblanc E, Li H, Munuganti RS, Frewin K, Rennie PS, Cherkasov A. Ban F, et al. Among authors: rennie ps. J Med Chem. 2014 Aug 14;57(15):6867-72. doi: 10.1021/jm500684r. Epub 2014 Jul 25. J Med Chem. 2014. PMID: 25025737

5

Discovery of small-molecule inhibitors selectively targeting the DNA-binding domain of the human androgen receptor.

Li H, Ban F, Dalal K, Leblanc E, Frewin K, Ma D, Adomat H, Rennie PS, Cherkasov A. Li H, et al. Among authors: rennie ps. J Med Chem. 2014 Aug 14;57(15):6458-67. doi: 10.1021/jm500802j. Epub 2014 Aug 4. J Med Chem. 2014. PMID: 25062331

6

Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.

Dalal K, Roshan-Moniri M, Sharma A, Li H, Ban F, Hessein M, Hsing M, Singh K, LeBlanc E, Dehm S, Tomlinson Guns ES, Cherkasov A, Rennie PS. Dalal K, et al. Among authors: rennie ps. J Biol Chem. 2014 Sep 19;289(38):26417-26429. doi: 10.1074/jbc.M114.553818. Epub 2014 Aug 1. J Biol Chem. 2014. PMID: 25086042 Free PMC article.

7

Drug-Discovery Pipeline for Novel Inhibitors of the Androgen Receptor.

Dalal K, Munuganti R, Morin H, Lallous N, Rennie PS, Cherkasov A. Dalal K, et al. Among authors: rennie ps. Methods Mol Biol. 2016;1443:31-54. doi: 10.1007/978-1-4939-3724-0_4. Methods Mol Biol. 2016. PMID: 27246333

8

Cheminformatics Modeling of Adverse Drug Responses by Clinically Relevant Mutants of Human Androgen Receptor.

Paul N, Carabet LA, Lallous N, Yamazaki T, Gleave ME, Rennie PS, Cherkasov A. Paul N, et al. Among authors: rennie ps. J Chem Inf Model. 2016 Dec 27;56(12):2507-2516. doi: 10.1021/acs.jcim.6b00400. Epub 2016 Nov 18. J Chem Inf Model. 2016. PMID: 28024400

9

Best Practices of Computer-Aided Drug Discovery: Lessons Learned from the Development of a Preclinical Candidate for Prostate Cancer with a New Mechanism of Action.

Ban F, Dalal K, Li H, LeBlanc E, Rennie PS, Cherkasov A. Ban F, et al. Among authors: rennie ps. J Chem Inf Model. 2017 May 22;57(5):1018-1028. doi: 10.1021/acs.jcim.7b00137. Epub 2017 May 4. J Chem Inf Model. 2017. PMID: 28441481

10

Bypassing Drug Resistance Mechanisms of Prostate Cancer with Small Molecules that Target Androgen Receptor-Chromatin Interactions.

Dalal K, Che M, Que NS, Sharma A, Yang R, Lallous N, Borgmann H, Ozistanbullu D, Tse R, Ban F, Li H, Tam KJ, Roshan-Moniri M, LeBlanc E, Gleave ME, Gewirth DT, Dehm SM, Cherkasov A, Rennie PS. Dalal K, et al. Among authors: rennie ps. Mol Cancer Ther. 2017 Oct;16(10):2281-2291. doi: 10.1158/1535-7163.MCT-17-0259. Epub 2017 Aug 3. Mol Cancer Ther. 2017. PMID: 28775145 Free PMC article.

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