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Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.
Zaher H, Meyer zu Schwabedissen HE, Tirona RG, Cox ML, Obert LA, Agrawal N, Palandra J, Stock JL, Kim RB, Ware JA. Zaher H, et al. Among authors: tirona rg. Mol Pharmacol. 2008 Aug;74(2):320-9. doi: 10.1124/mol.108.046458. Epub 2008 Apr 15. Mol Pharmacol. 2008. PMID: 18413659 Free PMC article.
Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis.
Meyer zu Schwabedissen HE, Ware JA, Finkelstein D, Chaudhry AS, Mansell S, Leon-Ponte M, Strom SC, Zaher H, Schwarz UI, Freeman DJ, Schuetz EG, Tirona RG, Kim RB. Meyer zu Schwabedissen HE, et al. Among authors: tirona rg. Hepatology. 2011 Aug;54(2):644-54. doi: 10.1002/hep.24391. Epub 2011 Jun 26. Hepatology. 2011. PMID: 21538436 Free PMC article.
96 results