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Page 1
Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.
Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, Guichou JF, Drucbert AS, Foulon C, Magnez R, Thuru X, Corvaisier M, Huet G, Chavatte P, Melnyk P, Bailly F, Cotelle P. Gibault F, et al. Among authors: thuru x. Cancers (Basel). 2018 May 8;10(5):140. doi: 10.3390/cancers10050140. Cancers (Basel). 2018. PMID: 29738494 Free PMC article.
Synthesis and Biological Evaluation of N-[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity.
Segaoula Z, Leclercq J, Verones V, Flouquet N, Lecoeur M, Ach L, Renault N, Barczyk A, Melnyk P, Berthelot P, Thuru X, Lebegue N. Segaoula Z, et al. Among authors: thuru x. J Med Chem. 2016 Sep 22;59(18):8422-40. doi: 10.1021/acs.jmedchem.6b00847. Epub 2016 Aug 30. J Med Chem. 2016. PMID: 27538123 Free article.
PD-1/PD-L1 binding studies using microscale thermophoresis.
Magnez R, Thiroux B, Taront S, Segaoula Z, Quesnel B, Thuru X. Magnez R, et al. Among authors: thuru x. Sci Rep. 2017 Dec 15;7(1):17623. doi: 10.1038/s41598-017-17963-1. Sci Rep. 2017. PMID: 29247197 Free PMC article.
MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis.
Liberelle M, Magnez R, Thuru X, Bencheikh Y, Ravez S, Quenon C, Drucbert AS, Foulon C, Melnyk P, Van Seuningen I, Lebègue N. Liberelle M, et al. Among authors: thuru x. Sci Rep. 2019 Nov 13;9(1):16678. doi: 10.1038/s41598-019-53099-0. Sci Rep. 2019. PMID: 31723153 Free PMC article.
The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis.
Stoup N, Liberelle M, Schulz C, Cavdarli S, Vasseur R, Magnez R, Lahdaoui F, Skrypek N, Peretti F, Frénois F, Thuru X, Melnyk P, Renault N, Jonckheere N, Lebègue N, Van Seuningen I. Stoup N, et al. Among authors: thuru x. Cancers (Basel). 2021 Nov 16;13(22):5746. doi: 10.3390/cancers13225746. Cancers (Basel). 2021. PMID: 34830899 Free PMC article.
Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction.
Le Biannic R, Magnez R, Klupsch F, Leleu-Chavain N, Thiroux B, Tardy M, El Bouazzati H, Dezitter X, Renault N, Vergoten G, Bailly C, Quesnel B, Thuru X, Millet R. Le Biannic R, et al. Among authors: thuru x. Eur J Med Chem. 2022 Jun 5;236:114343. doi: 10.1016/j.ejmech.2022.114343. Epub 2022 Apr 4. Eur J Med Chem. 2022. PMID: 35429911
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