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Interleukin-1β Activates a MYC-Dependent Metabolic Switch in Kidney Stromal Cells Necessary for Progressive Tubulointerstitial Fibrosis.
Lemos DR, McMurdo M, Karaca G, Wilflingseder J, Leaf IA, Gupta N, Miyoshi T, Susa K, Johnson BG, Soliman K, Wang G, Morizane R, Bonventre JV, Duffield JS. Lemos DR, et al. Among authors: karaca g. J Am Soc Nephrol. 2018 Jun;29(6):1690-1705. doi: 10.1681/ASN.2017121283. Epub 2018 May 8. J Am Soc Nephrol. 2018. PMID: 29739813 Free PMC article.
Role of Fn14 in acute alcoholic steatohepatitis in mice.
Karaca G, Xie G, Moylan C, Swiderska-Syn M, Guy CD, Krüger L, Machado MV, Choi SS, Michelotti GA, Burkly LC, Diehl AM. Karaca G, et al. Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15;308(4):G325-34. doi: 10.1152/ajpgi.00429.2013. Epub 2014 Dec 18. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25524063 Free PMC article.
Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis.
Machado MV, Michelotti GA, Pereira Tde A, Boursier J, Kruger L, Swiderska-Syn M, Karaca G, Xie G, Guy CD, Bohinc B, Lindblom KR, Johnson E, Kornbluth S, Diehl AM. Machado MV, et al. Among authors: karaca g. Gut. 2015 Jul;64(7):1148-57. doi: 10.1136/gutjnl-2014-307362. Epub 2014 Jul 22. Gut. 2015. PMID: 25053716 Free PMC article.
Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis.
Syn WK, Choi SS, Liaskou E, Karaca GF, Agboola KM, Oo YH, Mi Z, Pereira TA, Zdanowicz M, Malladi P, Chen Y, Moylan C, Jung Y, Bhattacharya SD, Teaberry V, Omenetti A, Abdelmalek MF, Guy CD, Adams DH, Kuo PC, Michelotti GA, Whitington PF, Diehl AM. Syn WK, et al. Hepatology. 2011 Jan;53(1):106-15. doi: 10.1002/hep.23998. Epub 2010 Oct 21. Hepatology. 2011. PMID: 20967826 Free PMC article.
Smoothened is a master regulator of adult liver repair.
Michelotti GA, Xie G, Swiderska M, Choi SS, Karaca G, Krüger L, Premont R, Yang L, Syn WK, Metzger D, Diehl AM. Michelotti GA, et al. Among authors: karaca g. J Clin Invest. 2013 Jun;123(6):2380-94. doi: 10.1172/JCI66904. J Clin Invest. 2013. PMID: 23563311 Free PMC article.
146 results