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Interleukin-18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin-18 transgenic mice.
Ishikura T, Kanai T, Uraushihara K, Iiyama R, Makita S, Totsuka T, Yamazaki M, Sawada T, Nakamura T, Miyata T, Kitahora T, Hibi T, Hoshino T, Watanabe M. Ishikura T, et al. Among authors: watanabe m. J Gastroenterol Hepatol. 2003 Aug;18(8):960-9. doi: 10.1046/j.1440-1746.2003.03097.x. J Gastroenterol Hepatol. 2003. PMID: 12859727
Macrophage-derived IL-18 targeting for the treatment of Crohn's disease.
Kanai T, Uraushihara K, Totsuka T, Okazawa A, Hibi T, Oshima S, Miyata T, Nakamura T, Watanabe M. Kanai T, et al. Among authors: watanabe m. Curr Drug Targets Inflamm Allergy. 2003 Jun;2(2):131-6. doi: 10.2174/1568010033484250. Curr Drug Targets Inflamm Allergy. 2003. PMID: 14561165 Review.
IL-7 exacerbates chronic colitis with expansion of memory IL-7Rhigh CD4+ mucosal T cells in mice.
Okada E, Yamazaki M, Tanabe M, Takeuchi T, Nanno M, Oshima S, Okamoto R, Tsuchiya K, Nakamura T, Kanai T, Hibi T, Watanabe M. Okada E, et al. Among authors: watanabe m. Am J Physiol Gastrointest Liver Physiol. 2005 Apr;288(4):G745-54. doi: 10.1152/ajpgi.00276.2004. Epub 2004 Nov 18. Am J Physiol Gastrointest Liver Physiol. 2005. PMID: 15550560 Free article.
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