Jäntti MH - Search Results

1

Anticancer activity of the protein kinase C modulator HMI-1a3 in 2D and 3D cell culture models of androgen-responsive and androgen-unresponsive prostate cancer.

Jäntti MH, Talman V, Räsänen K, Tarvainen I, Koistinen H, Tuominen RK. Jäntti MH, et al. FEBS Open Bio. 2018 Apr 17;8(5):817-828. doi: 10.1002/2211-5463.12419. eCollection 2018 May. FEBS Open Bio. 2018. PMID: 29744295 Free PMC article.

2

Protein Kinase C Activation as a Potential Therapeutic Strategy in Alzheimer's Disease: Is there a Role for Embryonic Lethal Abnormal Vision-like Proteins?

Talman V, Pascale A, Jäntti M, Amadio M, Tuominen RK. Talman V, et al. Basic Clin Pharmacol Toxicol. 2016 Aug;119(2):149-60. doi: 10.1111/bcpt.12581. Epub 2016 Apr 29. Basic Clin Pharmacol Toxicol. 2016. PMID: 27001133 Free article. Review.

3

Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C.

Provenzani R, Tarvainen I, Brandoli G, Lempinen A, Artes S, Turku A, Jäntti MH, Talman V, Yli-Kauhaluoma J, Tuominen RK, Boije Af Gennäs G. Provenzani R, et al. Among authors: jantti mh. PLoS One. 2018 Apr 11;13(4):e0195668. doi: 10.1371/journal.pone.0195668. eCollection 2018. PLoS One. 2018. PMID: 29641588 Free PMC article.

4

Protein kinase C -activating isophthalate derivatives mitigate Alzheimer's disease-related cellular alterations.

Sarajärvi T, Jäntti M, Paldanius KMA, Natunen T, Wu JC, Mäkinen P, Tarvainen I, Tuominen RK, Talman V, Hiltunen M. Sarajärvi T, et al. Neuropharmacology. 2018 Oct;141:76-88. doi: 10.1016/j.neuropharm.2018.08.020. Epub 2018 Aug 21. Neuropharmacology. 2018. PMID: 30138694

5

Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics.

Tarvainen I, Zimmermann T, Heinonen P, Jäntti MH, Yli-Kauhaluoma J, Talman V, Franzyk H, Tuominen RK, Christensen SB. Tarvainen I, et al. Among authors: jantti mh. ACS Med Chem Lett. 2019 Dec 23;11(5):671-677. doi: 10.1021/acsmedchemlett.9b00554. eCollection 2020 May 14. ACS Med Chem Lett. 2019. PMID: 32435369 Free PMC article.

6

Protein Kinase A-Mediated Effects of Protein Kinase C Partial Agonist 5-(Hydroxymethyl)Isophthalate 1a3 in Colorectal Cancer Cells.

Tarvainen I, Nunn RC, Tuominen RK, Jäntti MH, Talman V. Tarvainen I, et al. Among authors: jantti mh. J Pharmacol Exp Ther. 2022 Jan;380(1):54-62. doi: 10.1124/jpet.121.000848. Epub 2021 Oct 25. J Pharmacol Exp Ther. 2022. PMID: 34697230

7

Prolyl Oligopeptidase Regulates Dopamine Transporter Oligomerization and Phosphorylation in a PKC- and ERK-Independent Manner.

Julku UH, Jäntti M, Svarcbahs R, Myöhänen TT. Julku UH, et al. Int J Mol Sci. 2021 Feb 10;22(4):1777. doi: 10.3390/ijms22041777. Int J Mol Sci. 2021. PMID: 33579026 Free PMC article.

8

New tricks of prolyl oligopeptidase inhibitors - A common drug therapy for several neurodegenerative diseases.

Svarcbahs R, Julku U, Kilpeläinen T, Kyyrö M, Jäntti M, Myöhänen TT. Svarcbahs R, et al. Biochem Pharmacol. 2019 Mar;161:113-120. doi: 10.1016/j.bcp.2019.01.013. Epub 2019 Jan 17. Biochem Pharmacol. 2019. PMID: 30660495 Review.

9

Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A.

Svarcbahs R, Jäntti M, Kilpeläinen T, Julku UH, Urvas L, Kivioja S, Norrbacka S, Myöhänen TT. Svarcbahs R, et al. Pharmacol Res. 2020 Jan;151:104558. doi: 10.1016/j.phrs.2019.104558. Epub 2019 Nov 20. Pharmacol Res. 2020. PMID: 31759088

10

Prolyl oligopeptidase inhibition reduces oxidative stress via reducing NADPH oxidase activity by activating protein phosphatase 2A.

Eteläinen T, Kulmala V, Svarcbahs R, Jäntti M, Myöhänen TT. Eteläinen T, et al. Free Radic Biol Med. 2021 Jun;169:14-23. doi: 10.1016/j.freeradbiomed.2021.04.001. Epub 2021 Apr 7. Free Radic Biol Med. 2021. PMID: 33838285 Free article.

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