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Page 1
hIAPP forms toxic oligomers in plasma.
Rodriguez Camargo DC , Garg D , Buday K , Franko A , Rodriguez Camargo A , Schmidt F , Cox SJ , Suladze S , Haslbeck M , Mideksa YG , Gemmecker G , Aichler M , Mettenleiter G , Schulz M , Walch AK , Hrabě de Angelis M , Feige MJ , Sierra CA , Conrad M , Tripsianes K , Ramamoorthy A , Reif B . Rodriguez Camargo DC , et al. Among authors: walch ak. Chem Commun (Camb). 2018 May 24;54(43):5426-5429. doi: 10.1039/c8cc03097a. Chem Commun (Camb). 2018. PMID: 29745410 Free PMC article.
The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes.
Rodriguez Camargo DC, Tripsianes K, Buday K, Franko A, Göbl C, Hartlmüller C, Sarkar R, Aichler M, Mettenleiter G, Schulz M, Böddrich A, Erck C, Martens H, Walch AK, Madl T, Wanker EE, Conrad M, de Angelis MH, Reif B. Rodriguez Camargo DC, et al. Among authors: walch ak. Sci Rep. 2017 Mar 13;7:44041. doi: 10.1038/srep44041. Sci Rep. 2017. PMID: 28287098 Free PMC article.
N-acyl Taurines and Acylcarnitines Cause an Imbalance in Insulin Synthesis and Secretion Provoking β Cell Dysfunction in Type 2 Diabetes.
Aichler M, Borgmann D, Krumsiek J, Buck A, MacDonald PE, Fox JEM, Lyon J, Light PE, Keipert S, Jastroch M, Feuchtinger A, Mueller NS, Sun N, Palmer A, Alexandrov T, Hrabe de Angelis M, Neschen S, Tschöp MH, Walch A. Aichler M, et al. Cell Metab. 2017 Jun 6;25(6):1334-1347.e4. doi: 10.1016/j.cmet.2017.04.012. Cell Metab. 2017. PMID: 28591636 Free article.
Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.
Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M. Franko A, et al. Among authors: walch ak. Diabetes. 2016 Sep;65(9):2540-52. doi: 10.2337/db15-1670. Epub 2016 Jun 9. Diabetes. 2016. PMID: 27284107
Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.
Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, Roveri A, Peng X, Porto Freitas F, Seibt T, Mehr L, Aichler M, Walch A, Lamp D, Jastroch M, Miyamoto S, Wurst W, Ursini F, Arnér ESJ, Fradejas-Villar N, Schweizer U, Zischka H, Friedmann Angeli JP, Conrad M. Ingold I, et al. Cell. 2018 Jan 25;172(3):409-422.e21. doi: 10.1016/j.cell.2017.11.048. Epub 2017 Dec 28. Cell. 2018. PMID: 29290465 Free article.
321 results