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SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS.
Farrawell NE, Lambert-Smith I, Mitchell K, McKenna J, McAlary L, Ciryam P, Vine KL, Saunders DN, Yerbury JJ. Farrawell NE, et al. Among authors: lambert smith i. J Cell Sci. 2018 Jun 12;131(11):jcs209122. doi: 10.1242/jcs.209122. J Cell Sci. 2018. PMID: 29748379 Free PMC article.
Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS.
Ciryam P, Lambert-Smith IA, Bean DM, Freer R, Cid F, Tartaglia GG, Saunders DN, Wilson MR, Oliver SG, Morimoto RI, Dobson CM, Vendruscolo M, Favrin G, Yerbury JJ. Ciryam P, et al. Among authors: lambert smith ia. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E3935-E3943. doi: 10.1073/pnas.1613854114. Epub 2017 Apr 10. Proc Natl Acad Sci U S A. 2017. PMID: 28396410 Free PMC article.
Proteostasis impairment and ALS.
Lambert-Smith IA, Saunders DN, Yerbury JJ. Lambert-Smith IA, et al. Prog Biophys Mol Biol. 2022 Oct;174:3-27. doi: 10.1016/j.pbiomolbio.2022.06.001. Epub 2022 Jun 15. Prog Biophys Mol Biol. 2022. PMID: 35716729 Review.