Woo AY - Search Results

1

Synthesis and biological evaluation of β₂-adrenoceptor agonists bearing the 2-amino-2-phenylethanol scaffold.

Ge X, Woo AY, Xing G, Lu Y, Mo Y, Zhao Y, Lan Y, Li J, Yan H, Pan L, Zhang Y, Lin B, Cheng M. Ge X, et al. Among authors: woo ay. Eur J Med Chem. 2018 May 25;152:424-435. doi: 10.1016/j.ejmech.2018.04.041. Epub 2018 Apr 30. Eur J Med Chem. 2018. PMID: 29751236

2

Design, synthesis and biological evaluation of 5-(2-amino-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one derivatives as potent β₂-adrenoceptor agonists.

Xing G, Pan L, Yi C, Li X, Ge X, Zhao Y, Liu Y, Li J, Woo A, Lin B, Zhang Y, Cheng M. Xing G, et al. Bioorg Med Chem. 2019 Jun 15;27(12):2306-2314. doi: 10.1016/j.bmc.2018.10.043. Epub 2018 Nov 1. Bioorg Med Chem. 2019. PMID: 30392952

3

Discovery of β-arrestin-biased β₂-adrenoceptor agonists from 2-amino-2-phenylethanol derivatives.

Woo AY, Ge XY, Pan L, Xing G, Mo YM, Xing RJ, Li XR, Zhang YY, Wainer IW, Cheng MS, Xiao RP. Woo AY, et al. Acta Pharmacol Sin. 2019 Aug;40(8):1095-1105. doi: 10.1038/s41401-018-0200-x. Epub 2019 Jan 14. Acta Pharmacol Sin. 2019. PMID: 30643208 Free PMC article.

4

Design, synthesis and biological evaluation of 8-(2-amino-1-hydroxyethyl)-6-hydroxy-1,4-benzoxazine-3(4H)-one derivatives as potent β₂-adrenoceptor agonists.

Yi C, Xing G, Wang S, Li X, Liu Y, Li J, Lin B, Woo AY, Zhang Y, Pan L, Cheng M. Yi C, et al. Among authors: woo ay. Bioorg Med Chem. 2020 Jan 1;28(1):115178. doi: 10.1016/j.bmc.2019.115178. Epub 2019 Nov 11. Bioorg Med Chem. 2020. PMID: 31753798

5

Recent Advances in β₂-Agonists for Treatment of Chronic Respiratory Diseases and Heart Failure.

Xing G, Woo AY, Pan L, Lin B, Cheng MS. Xing G, et al. Among authors: woo ay. J Med Chem. 2020 Dec 24;63(24):15218-15242. doi: 10.1021/acs.jmedchem.0c01195. Epub 2020 Nov 19. J Med Chem. 2020. PMID: 33213146 Review.

6

Discovery of a Highly Selective β₂-Adrenoceptor Agonist with a 2-Amino-2-phenylethanol Scaffold as an Oral Antiasthmatic Agent.

Xing G, Li D, Woo AY, Zhi Z, Ji L, Xing R, Lv H, He B, An H, Zhao H, Lin B, Pan L, Cheng M. Xing G, et al. Among authors: woo ay. J Med Chem. 2022 Apr 14;65(7):5514-5527. doi: 10.1021/acs.jmedchem.1c02006. Epub 2022 Apr 1. J Med Chem. 2022. PMID: 35360904

7

Synthesis, biological evaluation and molecular modeling of 2-amino-2-phenylethanol derivatives as novel β₂-adrenoceptor agonists.

Ge X, Mo Y, Xing G, Ji L, Zhao H, Chen J, He B, Chen X, Xing R, Li X, Zhao Y, Li J, Yan H, Woo AY, Zhang Y, Lin B, Pan L, Cheng M. Ge X, et al. Among authors: woo ay. Bioorg Chem. 2018 Sep;79:155-162. doi: 10.1016/j.bioorg.2018.04.017. Epub 2018 Apr 26. Bioorg Chem. 2018. PMID: 29751321

8

Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of β2-adrenoceptor.

Woo AY, Jozwiak K, Toll L, Tanga MJ, Kozocas JA, Jimenez L, Huang Y, Song Y, Plazinska A, Pajak K, Paul RK, Bernier M, Wainer IW, Xiao RP. Woo AY, et al. J Biol Chem. 2014 Jul 11;289(28):19351-63. doi: 10.1074/jbc.M114.558882. Epub 2014 May 15. J Biol Chem. 2014. PMID: 24831005 Free PMC article.

9

Comparative molecular field analysis of fenoterol derivatives: A platform towards highly selective and effective beta(2)-adrenergic receptor agonists.

Jozwiak K, Woo AY, Tanga MJ, Toll L, Jimenez L, Kozocas JA, Plazinska A, Xiao RP, Wainer IW. Jozwiak K, et al. Among authors: woo ay. Bioorg Med Chem. 2010 Jan 15;18(2):728-36. doi: 10.1016/j.bmc.2009.11.062. Epub 2009 Dec 6. Bioorg Med Chem. 2010. PMID: 20036561 Free PMC article.

10

Biased β2-adrenoceptor signalling in heart failure: pathophysiology and drug discovery.

Woo AY, Song Y, Xiao RP, Zhu W. Woo AY, et al. Br J Pharmacol. 2015 Dec;172(23):5444-56. doi: 10.1111/bph.12965. Epub 2014 Dec 17. Br J Pharmacol. 2015. PMID: 25298054 Free PMC article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

41 results

Search Page

Filters