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Characterization of the Anti-Hepatitis C Virus Activity of New Nonpeptidic Small-Molecule Cyclophilin Inhibitors with the Potential for Broad Anti-Flaviviridae Activity.
Nevers Q, Ruiz I, Ahnou N, Donati F, Brillet R, Softic L, Chazal M, Jouvenet N, Fourati S, Baudesson C, Bruscella P, Gelin M, Guichou JF, Pawlotsky JM, Ahmed-Belkacem A. Nevers Q, et al. Among authors: guichou jf. Antimicrob Agents Chemother. 2018 Jun 26;62(7):e00126-18. doi: 10.1128/AAC.00126-18. Print 2018 Jul. Antimicrob Agents Chemother. 2018. PMID: 29760125 Free PMC article.
In-plate protein crystallization, in situ ligand soaking and X-ray diffraction.
le Maire A, Gelin M, Pochet S, Hoh F, Pirocchi M, Guichou JF, Ferrer JL, Labesse G. le Maire A, et al. Among authors: guichou jf. Acta Crystallogr D Biol Crystallogr. 2011 Sep;67(Pt 9):747-55. doi: 10.1107/S0907444911023249. Epub 2011 Aug 9. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21904027
Nuclear Envelope Protein SUN2 Promotes Cyclophilin-A-Dependent Steps of HIV Replication.
Lahaye X, Satoh T, Gentili M, Cerboni S, Silvin A, Conrad C, Ahmed-Belkacem A, Rodriguez EC, Guichou JF, Bosquet N, Piel M, Le Grand R, King MC, Pawlotsky JM, Manel N. Lahaye X, et al. Among authors: guichou jf. Cell Rep. 2016 Apr 26;15(4):879-892. doi: 10.1016/j.celrep.2016.03.074. Epub 2016 Apr 14. Cell Rep. 2016. PMID: 27149839 Free PMC article.
Small-Molecule Inhibitors of Cyclophilins Block Opening of the Mitochondrial Permeability Transition Pore and Protect Mice From Hepatic Ischemia/Reperfusion Injury.
Panel M, Ruiz I, Brillet R, Lafdil F, Teixeira-Clerc F, Nguyen CT, Calderaro J, Gelin M, Allemand F, Guichou JF, Ghaleh B, Ahmed-Belkacem A, Morin D, Pawlotsky JM. Panel M, et al. Among authors: guichou jf. Gastroenterology. 2019 Nov;157(5):1368-1382. doi: 10.1053/j.gastro.2019.07.026. Epub 2019 Jul 20. Gastroenterology. 2019. PMID: 31336123
Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs.
Liberelle M, Toulotte F, Renault N, Gelin M, Allemand F, Melnyk P, Guichou JF, Cotelle P. Liberelle M, et al. Among authors: guichou jf. J Med Chem. 2022 Apr 28;65(8):5926-5940. doi: 10.1021/acs.jmedchem.2c00075. Epub 2022 Apr 7. J Med Chem. 2022. PMID: 35389210 Review.
57 results