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A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.
Mele L, Paino F, Papaccio F, Regad T, Boocock D, Stiuso P, Lombardi A, Liccardo D, Aquino G, Barbieri A, Arra C, Coveney C, La Noce M, Papaccio G, Caraglia M, Tirino V, Desiderio V. Mele L, et al. Among authors: barbieri a. Cell Death Dis. 2018 May 1;9(5):572. doi: 10.1038/s41419-018-0635-5. Cell Death Dis. 2018. PMID: 29760380 Free PMC article.
The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways.
Caraglia M, Marra M, Viscomi C, D'Alessandro AM, Budillon A, Meo G, Arra C, Barbieri A, Rapp UR, Baldi A, Tassone P, Venuta S, Abbruzzese A, Tagliaferri P. Caraglia M, et al. Among authors: barbieri a. Int J Cancer. 2007 Nov 15;121(10):2317-30. doi: 10.1002/ijc.22964. Int J Cancer. 2007. PMID: 17657738
Structure-based design of an urokinase-type plasminogen activator receptor-derived peptide inhibiting cell migration and lung metastasis.
Carriero MV, Longanesi-Cattani I, Bifulco K, Maglio O, Lista L, Barbieri A, Votta G, Masucci MT, Arra C, Franco R, De Rosa M, Stoppelli MP, Pavone V. Carriero MV, et al. Among authors: barbieri a. Mol Cancer Ther. 2009 Sep;8(9):2708-17. doi: 10.1158/1535-7163.MCT-09-0174. Epub 2009 Aug 25. Mol Cancer Ther. 2009. PMID: 19706734
CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy.
de Nigris F, Crudele V, Giovane A, Casamassimi A, Giordano A, Garban HJ, Cacciatore F, Pentimalli F, Marquez-Garban DC, Petrillo A, Cito L, Sommese L, Fiore A, Petrillo M, Siani A, Barbieri A, Arra C, Rengo F, Hayashi T, Al-Omran M, Ignarro LJ, Napoli C. de Nigris F, et al. Among authors: barbieri a. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14484-9. doi: 10.1073/pnas.1008256107. Epub 2010 Jul 26. Proc Natl Acad Sci U S A. 2010. PMID: 20660740 Free PMC article.
1,034 results