Bay-Jensen AC - Search Results

1

Is radiographic progression in radiographic axial spondyloarthritis related to matrix metalloproteinase degradation of extracellular matrix?

Siebuhr AS, van der Heijde D, Bay-Jensen AC, Karsdal MA, Landewé R, van Tubergen A, Ramiro S. Siebuhr AS, et al. RMD Open. 2018 May 14;4(1):e000648. doi: 10.1136/rmdopen-2018-000648. eCollection 2018. RMD Open. 2018. PMID: 29765702 Free PMC article.

2

Biochemical markers and the FDA Critical Path: how biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development.

Karsdal MA, Henriksen K, Leeming DJ, Mitchell P, Duffin K, Barascuk N, Klickstein L, Aggarwal P, Nemirovskiy O, Byrjalsen I, Qvist P, Bay-Jensen AC, Dam EB, Madsen SH, Christiansen C. Karsdal MA, et al. Biomarkers. 2009 May;14(3):181-202. doi: 10.1080/13547500902777608. Biomarkers. 2009. PMID: 19399662 Review.

3

Should biochemical markers of bone turnover be considered standard practice for safety pharmacology?

Henriksen K, Bohren KM, Bay-Jensen AC, Karsdal MA. Henriksen K, et al. Biomarkers. 2010 May;15(3):195-204. doi: 10.3109/13547500903434519. Biomarkers. 2010. PMID: 19951005

4

Biochemical markers identify influences on bone and cartilage degradation in osteoarthritis--the effect of sex, Kellgren-Lawrence (KL) score, body mass index (BMI), oral salmon calcitonin (sCT) treatment and diurnal variation.

Karsdal MA, Byrjalsen I, Bay-Jensen AC, Henriksen K, Riis BJ, Christiansen C. Karsdal MA, et al. BMC Musculoskelet Disord. 2010 Jun 17;11:125. doi: 10.1186/1471-2474-11-125. BMC Musculoskelet Disord. 2010. PMID: 20565725 Free PMC article. Clinical Trial.

5

Lessons learned from the development of oral calcitonin: the first tablet formulation of a protein in phase III clinical trials.

Karsdal MA, Henriksen K, Bay-Jensen AC, Molloy B, Arnold M, John MR, Byrjalsen I, Azria M, Riis BJ, Qvist P, Christiansen C. Karsdal MA, et al. J Clin Pharmacol. 2011 Apr;51(4):460-71. doi: 10.1177/0091270010372625. Epub 2010 Jul 21. J Clin Pharmacol. 2011. PMID: 20660294 Review.

6

Post-translational modifications of the extracellular matrix are key events in cancer progression: opportunities for biochemical marker development.

Leeming DJ, Bay-Jensen AC, Vassiliadis E, Larsen MR, Henriksen K, Karsdal MA. Leeming DJ, et al. Biomarkers. 2011 May;16(3):193-205. doi: 10.3109/1354750X.2011.557440. Biomarkers. 2011. PMID: 21506694 Review.

7

Investigation of two novel biochemical markers of inflammation, matrix metalloproteinase and cathepsin generated fragments of C-reactive protein, in patients with ankylosing spondylitis.

Skjøt-Arkil H, Schett G, Zhang C, Larsen DV, Wang Y, Zheng Q, Larsen MR, Nawrocki A, Bay-Jensen AC, Henriksen K, Christiansen C, Alexandersen P, Leeming DJ, Karsdal MA. Skjøt-Arkil H, et al. Clin Exp Rheumatol. 2012 May-Jun;30(3):371-9. Epub 2012 Jun 26. Clin Exp Rheumatol. 2012. PMID: 22339813

8

Oral salmon calcitonin attenuates hyperglycaemia and preserves pancreatic beta-cell area and function in Zucker diabetic fatty rats.

Feigh M, Andreassen KV, Neutzsky-Wulff AV, Petersen ST, Hansen C, Bay-Jensen AC, Henriksen JE, Beck-Nielsen H, Christiansen C, Henriksen K, Karsdal MA. Feigh M, et al. Br J Pharmacol. 2012 Sep;167(1):151-63. doi: 10.1111/j.1476-5381.2012.01979.x. Br J Pharmacol. 2012. PMID: 22506938 Free PMC article.

9

Matrix metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis.

Siebuhr AS, Wang J, Karsdal M, Bay-Jensen AC, Y J, Q Z. Siebuhr AS, et al. J Transl Med. 2012 Sep 20;10:195. doi: 10.1186/1479-5876-10-195. J Transl Med. 2012. PMID: 22992383 Free PMC article.

10

The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet?

Karsdal MA, Bay-Jensen AC, Henriksen K, Christiansen C. Karsdal MA, et al. Menopause Int. 2012 Dec;18(4):139-46. doi: 10.1258/mi.2012.012025. Epub 2012 Sep 28. Menopause Int. 2012. PMID: 23024184 Review.

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