Wang K - Search Results

1

Striking a Balance between Carbonate/Carbamate Linkage Bond- and Reduction-Sensitive Disulfide Bond-Bearing Linker for Tailored Controlled Release: In Situ Covalent-Albumin-Binding Gemcitabine Prodrugs Promote Bioavailability and Tumor Accumulation.

Zhang H, Wang K, Na K, Li D, Li Z, Zhao D, Zhong L, Wang M, Kou L, Luo C, Zhang H, Kan Q, Ding H, He Z, Sun J. Zhang H, et al. Among authors: wang k, wang m. J Med Chem. 2018 Jun 14;61(11):4904-4917. doi: 10.1021/acs.jmedchem.8b00293. Epub 2018 May 24. J Med Chem. 2018. PMID: 29768008

2

Multifunctional Tumor-Targeting Cathepsin B-Sensitive Gemcitabine Prodrug Covalently Targets Albumin in Situ and Improves Cancer Therapy.

Zhang H, Sun Z, Wang K, Li N, Chen H, Tan X, Li L, He Z, Sun J. Zhang H, et al. Among authors: wang k. Bioconjug Chem. 2018 Jun 20;29(6):1852-1858. doi: 10.1021/acs.bioconjchem.8b00223. Epub 2018 May 24. Bioconjug Chem. 2018. PMID: 29775284

3

The current strategies of optimization of oseltamivir against mutant neuraminidases of influenza A：A review.

Wang K, Zhang H, Tian Y. Wang K, et al. Eur J Med Chem. 2022 Dec 5;243:114711. doi: 10.1016/j.ejmech.2022.114711. Epub 2022 Aug 28. Eur J Med Chem. 2022. PMID: 36055001 Review.

4

Discovery of a non-zwitterionic oseltamivir analogue as a potent influenza a neuraminidase inhibitor.

Zhang H, Wang K, Zhu H, Zhao X, Zhao H, Lei Z, Chen B, Yang F, Liu K, Zhang K, Wang J, Tian Y. Zhang H, et al. Among authors: wang k, wang j. Eur J Med Chem. 2020 Aug 15;200:112423. doi: 10.1016/j.ejmech.2020.112423. Epub 2020 May 12. Eur J Med Chem. 2020. PMID: 32512482

5

Discovery of hydrazide-containing oseltamivir analogues as potent inhibitors of influenza A neuraminidase.

Zhao H, Jiang S, Ye Z, Zhu H, Hu B, Meng P, Hu Y, Zhang H, Wang K, Wang J, Tian Y. Zhao H, et al. Among authors: wang k, wang j. Eur J Med Chem. 2021 Oct 5;221:113567. doi: 10.1016/j.ejmech.2021.113567. Epub 2021 May 23. Eur J Med Chem. 2021. PMID: 34082224

6

Design, synthesis and biological evaluation of oseltamivir derivatives containing pyridyl group as potent inhibitors of neuraminidase for influenza A.

Wang K, Lei Z, Zhao L, Chen B, Yang F, Liu K, Zhu H, Zhao H, Cao R, Zhang K, Tian Y. Wang K, et al. Eur J Med Chem. 2020 Jan 1;185:111841. doi: 10.1016/j.ejmech.2019.111841. Epub 2019 Nov 2. Eur J Med Chem. 2020. PMID: 31708183

7

Design, synthesis, and evaluation of carboxyl-modified oseltamivir derivatives with improved lipophilicity as neuraminidase inhibitors.

Wang B, Wang K, Meng P, Hu Y, Yang F, Liu K, Lei Z, Chen B, Tian Y. Wang B, et al. Among authors: wang k. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3477-3482. doi: 10.1016/j.bmcl.2018.09.014. Epub 2018 Sep 12. Bioorg Med Chem Lett. 2018. PMID: 30266543

8

Application of carbamyl in structural optimization.

Wang K, Zhu H, Zhao H, Zhang K, Tian Y. Wang K, et al. Bioorg Chem. 2020 May;98:103757. doi: 10.1016/j.bioorg.2020.103757. Epub 2020 Mar 13. Bioorg Chem. 2020. PMID: 32217370 Review.

9

Synthesis and biological evaluation of NH₂-acyl oseltamivir analogues as potent neuraminidase inhibitors.

Wang K, Yang F, Wang L, Liu K, Sun L, Lin B, Hu Y, Wang B, Cheng M, Tian Y. Wang K, et al. Among authors: wang l, wang b. Eur J Med Chem. 2017 Dec 1;141:648-656. doi: 10.1016/j.ejmech.2017.10.004. Epub 2017 Oct 5. Eur J Med Chem. 2017. PMID: 29107426

10

Synthesis and characterization of a PAMAM-OH derivative containing an acid-labile β-thiopropionate bond for gene delivery.

Chen K, Chen Q, Wang K, Zhu J, Li W, Li W, Qiu L, Guan G, Qiao M, Zhao X, Hu H, Chen D. Chen K, et al. Among authors: wang k. Int J Pharm. 2016 Jul 25;509(1-2):314-327. doi: 10.1016/j.ijpharm.2016.05.060. Epub 2016 May 31. Int J Pharm. 2016. PMID: 27260132

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