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DNA methylation differences at the glucocorticoid receptor gene in depression are related to functional alterations in hypothalamic-pituitary-adrenal axis activity and to early life emotional abuse.
Farrell C, Doolin K, O' Leary N, Jairaj C, Roddy D, Tozzi L, Morris D, Harkin A, Frodl T, Nemoda Z, Szyf M, Booij L, O'Keane V. Farrell C, et al. Among authors: tozzi l. Psychiatry Res. 2018 Jul;265:341-348. doi: 10.1016/j.psychres.2018.04.064. Epub 2018 May 8. Psychiatry Res. 2018. PMID: 29793048
A Cognitive Biotype of Depression and Symptoms, Behavior Measures, Neural Circuits, and Differential Treatment Outcomes: A Prespecified Secondary Analysis of a Randomized Clinical Trial.
Hack LM, Tozzi L, Zenteno S, Olmsted AM, Hilton R, Jubeir J, Korgaonkar MS, Schatzberg AF, Yesavage JA, O'Hara R, Williams LM. Hack LM, et al. Among authors: tozzi l. JAMA Netw Open. 2023 Jun 1;6(6):e2318411. doi: 10.1001/jamanetworkopen.2023.18411. JAMA Netw Open. 2023. PMID: 37318808 Free PMC article. Clinical Trial.
Childhood adversity impacts on brain subcortical structures relevant to depression.
Frodl T, Janowitz D, Schmaal L, Tozzi L, Dobrowolny H, Stein DJ, Veltman DJ, Wittfeld K, van Erp TGM, Jahanshad N, Block A, Hegenscheid K, Völzke H, Lagopoulos J, Hatton SN, Hickie IB, Frey EM, Carballedo A, Brooks SJ, Vuletic D, Uhlmann A, Veer IM, Walter H, Schnell K, Grotegerd D, Arolt V, Kugel H, Schramm E, Konrad C, Zurowski B, Baune BT, van der Wee NJA, van Tol MJ, Penninx BWJH, Thompson PM, Hibar DP, Dannlowski U, Grabe HJ. Frodl T, et al. Among authors: tozzi l. J Psychiatr Res. 2017 Mar;86:58-65. doi: 10.1016/j.jpsychires.2016.11.010. Epub 2016 Nov 19. J Psychiatr Res. 2017. PMID: 27918926 Free PMC article.
136 results