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Genetic Variation of the SusC/SusD Homologs from a Polysaccharide Utilization Locus Underlies Divergent Fructan Specificities and Functional Adaptation in Bacteroides thetaiotaomicron Strains.
Joglekar P, Sonnenburg ED, Higginbottom SK, Earle KA, Morland C, Shapiro-Ward S, Bolam DN, Sonnenburg JL. Joglekar P, et al. Among authors: higginbottom sk. mSphere. 2018 May 23;3(3):e00185-18. doi: 10.1128/mSphereDirect.00185-18. eCollection 2018 May-Jun. mSphere. 2018. PMID: 29794055 Free PMC article.
Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice.
Kashyap PC, Marcobal A, Ursell LK, Larauche M, Duboc H, Earle KA, Sonnenburg ED, Ferreyra JA, Higginbottom SK, Million M, Tache Y, Pasricha PJ, Knight R, Farrugia G, Sonnenburg JL. Kashyap PC, et al. Among authors: higginbottom sk. Gastroenterology. 2013 May;144(5):967-77. doi: 10.1053/j.gastro.2013.01.047. Epub 2013 Feb 1. Gastroenterology. 2013. PMID: 23380084 Free PMC article.
Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota.
Kashyap PC, Marcobal A, Ursell LK, Smits SA, Sonnenburg ED, Costello EK, Higginbottom SK, Domino SE, Holmes SP, Relman DA, Knight R, Gordon JI, Sonnenburg JL. Kashyap PC, et al. Among authors: higginbottom sk. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17059-64. doi: 10.1073/pnas.1306070110. Epub 2013 Sep 23. Proc Natl Acad Sci U S A. 2013. PMID: 24062455 Free PMC article.
A small-molecule antivirulence agent for treating Clostridium difficile infection.
Bender KO, Garland M, Ferreyra JA, Hryckowian AJ, Child MA, Puri AW, Solow-Cordero DE, Higginbottom SK, Segal E, Banaei N, Shen A, Sonnenburg JL, Bogyo M. Bender KO, et al. Among authors: higginbottom sk. Sci Transl Med. 2015 Sep 23;7(306):306ra148. doi: 10.1126/scitranslmed.aac9103. Epub 2015 Sep 23. Sci Transl Med. 2015. PMID: 26400909 Free PMC article.
34 results