Levy JM - Search Results

1

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction.

Koblan LW, Doman JL, Wilson C, Levy JM, Tay T, Newby GA, Maianti JP, Raguram A, Liu DR. Koblan LW, et al. Among authors: levy jm. Nat Biotechnol. 2018 Oct;36(9):843-846. doi: 10.1038/nbt.4172. Epub 2018 May 29. Nat Biotechnol. 2018. PMID: 29813047 Free PMC article.

2

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions.

Kim YB, Komor AC, Levy JM, Packer MS, Zhao KT, Liu DR. Kim YB, et al. Among authors: levy jm. Nat Biotechnol. 2017 Apr;35(4):371-376. doi: 10.1038/nbt.3803. Epub 2017 Feb 13. Nat Biotechnol. 2017. PMID: 28191901 Free PMC article.

3

Continuous evolution of base editors with expanded target compatibility and improved activity.

Thuronyi BW, Koblan LW, Levy JM, Yeh WH, Zheng C, Newby GA, Wilson C, Bhaumik M, Shubina-Oleinik O, Holt JR, Liu DR. Thuronyi BW, et al. Among authors: levy jm. Nat Biotechnol. 2019 Sep;37(9):1070-1079. doi: 10.1038/s41587-019-0193-0. Epub 2019 Jul 22. Nat Biotechnol. 2019. PMID: 31332326 Free PMC article.

4

Publisher Correction: Continuous evolution of base editors with expanded target compatibility and improved activity.

Thuronyi BW, Koblan LW, Levy JM, Yeh WH, Zheng C, Newby GA, Wilson C, Bhaumik M, Shubina-Oleinik O, Holt JR, Liu DR. Thuronyi BW, et al. Among authors: levy jm. Nat Biotechnol. 2019 Sep;37(9):1091. doi: 10.1038/s41587-019-0253-5. Nat Biotechnol. 2019. PMID: 31406330

5

Search-and-replace genome editing without double-strand breaks or donor DNA.

Anzalone AV, Randolph PB, Davis JR, Sousa AA, Koblan LW, Levy JM, Chen PJ, Wilson C, Newby GA, Raguram A, Liu DR. Anzalone AV, et al. Among authors: levy jm. Nature. 2019 Dec;576(7785):149-157. doi: 10.1038/s41586-019-1711-4. Epub 2019 Oct 21. Nature. 2019. PMID: 31634902 Free PMC article.

6

Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses.

Levy JM, Yeh WH, Pendse N, Davis JR, Hennessey E, Butcher R, Koblan LW, Comander J, Liu Q, Liu DR. Levy JM, et al. Nat Biomed Eng. 2020 Jan;4(1):97-110. doi: 10.1038/s41551-019-0501-5. Epub 2020 Jan 14. Nat Biomed Eng. 2020. PMID: 31937940 Free PMC article.

7

In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness.

Yeh WH, Shubina-Oleinik O, Levy JM, Pan B, Newby GA, Wornow M, Burt R, Chen JC, Holt JR, Liu DR. Yeh WH, et al. Among authors: levy jm. Sci Transl Med. 2020 Jun 3;12(546):eaay9101. doi: 10.1126/scitranslmed.aay9101. Sci Transl Med. 2020. PMID: 32493795 Free PMC article.

8

In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.

Koblan LW, Erdos MR, Wilson C, Cabral WA, Levy JM, Xiong ZM, Tavarez UL, Davison LM, Gete YG, Mao X, Newby GA, Doherty SP, Narisu N, Sheng Q, Krilow C, Lin CY, Gordon LB, Cao K, Collins FS, Brown JD, Liu DR. Koblan LW, et al. Among authors: levy jm. Nature. 2021 Jan;589(7843):608-614. doi: 10.1038/s41586-020-03086-7. Epub 2021 Jan 6. Nature. 2021. PMID: 33408413 Free PMC article.

9

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing.

Anzalone AV, Gao XD, Podracky CJ, Nelson AT, Koblan LW, Raguram A, Levy JM, Mercer JAM, Liu DR. Anzalone AV, et al. Among authors: levy jm. Nat Biotechnol. 2022 May;40(5):731-740. doi: 10.1038/s41587-021-01133-w. Epub 2021 Dec 9. Nat Biotechnol. 2022. PMID: 34887556 Free PMC article.

10

Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors.

Davis JR, Wang X, Witte IP, Huang TP, Levy JM, Raguram A, Banskota S, Seidah NG, Musunuru K, Liu DR. Davis JR, et al. Among authors: levy jm. Nat Biomed Eng. 2022 Nov;6(11):1272-1283. doi: 10.1038/s41551-022-00911-4. Epub 2022 Jul 28. Nat Biomed Eng. 2022. PMID: 35902773 Free PMC article.

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