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Simvastatin interferes with cancer 'stem-cell' plasticity reducing metastasis in ovarian cancer.
Kato S, Liberona MF, Cerda-Infante J, Sánchez M, Henríquez J, Bizama C, Bravo ML, Gonzalez P, Gejman R, Brañes J, García K, Ibañez C, Owen GI, Roa JC, Montecinos V, Cuello MA. Kato S, et al. Among authors: bizama c. Endocr Relat Cancer. 2018 Oct;25(10):821-836. doi: 10.1530/ERC-18-0132. Epub 2018 May 30. Endocr Relat Cancer. 2018. PMID: 29848667
Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice.
Weber H, Leal P, Stein S, Kunkel H, García P, Bizama C, Espinoza JA, Riquelme I, Nervi B, Araya JC, Grez M, Roa JC. Weber H, et al. Among authors: bizama c. Oncotarget. 2015 Oct 13;6(31):31877-88. doi: 10.18632/oncotarget.5047. Oncotarget. 2015. PMID: 26397134 Free PMC article.
miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.
Riquelme I, Tapia O, Leal P, Sandoval A, Varga MG, Letelier P, Buchegger K, Bizama C, Espinoza JA, Peek RM, Araya JC, Roa JC. Riquelme I, et al. Among authors: bizama c. Cell Oncol (Dordr). 2016 Feb;39(1):23-33. doi: 10.1007/s13402-015-0247-3. Epub 2015 Oct 12. Cell Oncol (Dordr). 2016. PMID: 26458815 Free PMC article.
The inflammatory inception of gallbladder cancer.
Espinoza JA, Bizama C, García P, Ferreccio C, Javle M, Miquel JF, Koshiol J, Roa JC. Espinoza JA, et al. Among authors: bizama c. Biochim Biophys Acta. 2016 Apr;1865(2):245-54. doi: 10.1016/j.bbcan.2016.03.004. Epub 2016 Mar 12. Biochim Biophys Acta. 2016. PMID: 26980625 Free PMC article. Review.
Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.
Weber H, Valbuena JR, Barbhuiya MA, Stein S, Kunkel H, García P, Bizama C, Riquelme I, Espinoza JA, Kurtz SE, Tyner JW, Calderon JF, Corvalán AH, Grez M, Pandey A, Leal-Rojas P, Roa JC. Weber H, et al. Among authors: bizama c. Oncotarget. 2017 Apr 18;8(16):26169-26184. doi: 10.18632/oncotarget.15410. Oncotarget. 2017. PMID: 28412732 Free PMC article.
MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer.
Sandoval-Bórquez A, Polakovicova I, Carrasco-Véliz N, Lobos-González L, Riquelme I, Carrasco-Avino G, Bizama C, Norero E, Owen GI, Roa JC, Corvalán AH. Sandoval-Bórquez A, et al. Among authors: bizama c. Clin Epigenetics. 2017 Oct 17;9:114. doi: 10.1186/s13148-017-0413-8. eCollection 2017. Clin Epigenetics. 2017. PMID: 29075357 Free PMC article.
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