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Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells.
Fraietta JA, Nobles CL, Sammons MA, Lundh S, Carty SA, Reich TJ, Cogdill AP, Morrissette JJD, DeNizio JE, Reddy S, Hwang Y, Gohil M, Kulikovskaya I, Nazimuddin F, Gupta M, Chen F, Everett JK, Alexander KA, Lin-Shiao E, Gee MH, Liu X, Young RM, Ambrose D, Wang Y, Xu J, Jordan MS, Marcucci KT, Levine BL, Garcia KC, Zhao Y, Kalos M, Porter DL, Kohli RM, Lacey SF, Berger SL, Bushman FD, June CH, Melenhorst JJ. Fraietta JA, et al. Among authors: jordan ms. Nature. 2018 Jun;558(7709):307-312. doi: 10.1038/s41586-018-0178-z. Epub 2018 May 30. Nature. 2018. PMID: 29849141 Free PMC article.
Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways.
Kim JS, Sklarz T, Banks LB, Gohil M, Waickman AT, Skuli N, Krock BL, Luo CT, Hu W, Pollizzi KN, Li MO, Rathmell JC, Birnbaum MJ, Powell JD, Jordan MS, Koretzky GA. Kim JS, et al. Among authors: jordan ms. Nat Immunol. 2013 Jun;14(6):611-8. doi: 10.1038/ni.2607. Epub 2013 May 5. Nat Immunol. 2013. Retraction in: Nat Immunol. 2014 Oct;15(10):996. doi: 10.1038/ni0910-996 PMID: 23644504 Free PMC article. Retracted.
mTORC2 regulates multiple aspects of NKT-cell development and function.
Sklarz T, Guan P, Gohil M, Cotton RM, Ge MQ, Haczku A, Das R, Jordan MS. Sklarz T, et al. Among authors: jordan ms. Eur J Immunol. 2017 Mar;47(3):516-526. doi: 10.1002/eji.201646343. Epub 2017 Jan 27. Eur J Immunol. 2017. PMID: 28078715 Free PMC article.
65 results