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Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro.
Suwala AK, Koch K, Rios DH, Aretz P, Uhlmann C, Ogorek I, Felsberg J, Reifenberger G, Köhrer K, Deenen R, Steiger HJ, Kahlert UD, Maciaczyk J. Suwala AK, et al. Among authors: maciaczyk j. Oncotarget. 2018 Apr 27;9(32):22703-22716. doi: 10.18632/oncotarget.25210. eCollection 2018 Apr 27. Oncotarget. 2018. PMID: 29854309 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33563939
A comparative pharmaco-metabolomic study of glutaminase inhibitors in glioma stem-like cells confirms biological effectiveness but reveals differences in target-specificity.
Koch K, Hartmann R, Tsiampali J, Uhlmann C, Nickel AC, He X, Kamp MA, Sabel M, Barker RA, Steiger HJ, Hänggi D, Willbold D, Maciaczyk J, Kahlert UD. Koch K, et al. Among authors: maciaczyk j. Cell Death Discov. 2020 Apr 16;6:20. doi: 10.1038/s41420-020-0258-3. eCollection 2020. Cell Death Discov. 2020. PMID: 32337072 Free PMC article.
Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition.
Kahlert UD, Maciaczyk D, Doostkam S, Orr BA, Simons B, Bogiel T, Reithmeier T, Prinz M, Schubert J, Niedermann G, Brabletz T, Eberhart CG, Nikkhah G, Maciaczyk J. Kahlert UD, et al. Among authors: maciaczyk d, maciaczyk j. Cancer Lett. 2012 Dec 1;325(1):42-53. doi: 10.1016/j.canlet.2012.05.024. Epub 2012 May 28. Cancer Lett. 2012. PMID: 22652173
CD133/CD15 defines distinct cell subpopulations with differential in vitro clonogenic activity and stem cell-related gene expression profile in in vitro propagated glioblastoma multiforme-derived cell line with a PNET-like component.
Kahlert UD, Bender NO, Maciaczyk D, Bogiel T, Bar EE, Eberhart CG, Nikkhah G, Maciaczyk J. Kahlert UD, et al. Among authors: maciaczyk d, maciaczyk j. Folia Neuropathol. 2012;50(4):357-68. doi: 10.5114/fn.2012.32365. Folia Neuropathol. 2012. PMID: 23319191 Free article.
Resistance to hypoxia-induced, BNIP3-mediated cell death contributes to an increase in a CD133-positive cell population in human glioblastomas in vitro.
Kahlert UD, Maciaczyk D, Dai F, Claus R, Firat E, Doostkam S, Bogiel T, Carro MS, Döbrössy M, Herold-Mende C, Niedermann G, Prinz M, Nikkhah G, Maciaczyk J. Kahlert UD, et al. Among authors: maciaczyk d, maciaczyk j. J Neuropathol Exp Neurol. 2012 Dec;71(12):1086-99. doi: 10.1097/NEN.0b013e3182772d83. J Neuropathol Exp Neurol. 2012. PMID: 23147506
70 results