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Safety, tolerability and pharmacokinetics/pharmacodynamics of the adrenomedullin antibody adrecizumab in a first-in-human study and during experimental human endotoxaemia in healthy subjects.
Geven C, van Lier D, Blet A, Peelen R, Ten Elzen B, Mebazaa A, Kox M, Pickkers P. Geven C, et al. Among authors: van lier d. Br J Clin Pharmacol. 2018 Sep;84(9):2129-2141. doi: 10.1111/bcp.13655. Epub 2018 Jul 3. Br J Clin Pharmacol. 2018. PMID: 29856470 Free PMC article. Clinical Trial.
Monitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ failure and survival in sepsis: a prospective observational multinational study.
Blet A, Deniau B, Santos K, van Lier DPT, Azibani F, Wittebole X, Chousterman BG, Gayat E, Hartmann O, Struck J, Bergmann A, Antonelli M, Beishuizen A, Constantin JM, Damoisel C, Deye N, Di Somma S, Dugernier T, François B, Gaudry S, Huberlant V, Lascarrou JB, Marx G, Mercier E, Oueslati H, Pickkers P, Sonneville R, Legrand M, Laterre PF, Mebazaa A; AdrenOSS-1 Study Investigators. Blet A, et al. Crit Care. 2021 Feb 15;25(1):61. doi: 10.1186/s13054-021-03471-2. Crit Care. 2021. PMID: 33588925 Free PMC article.
High plasma dipeptidyl peptidase 3 levels are associated with mortality and organ failure in shock: results from the international, prospective and observational FROG-ICU cohort.
Deniau B, Picod A, Van Lier D, Vaittinada Ayar P, Santos K, Hartmann O, Gayat E, Mebazaa A, Blet A, Azibani F. Deniau B, et al. Among authors: van lier d. Br J Anaesth. 2022 Feb;128(2):e54-e57. doi: 10.1016/j.bja.2021.11.021. Epub 2021 Dec 8. Br J Anaesth. 2022. PMID: 34895716 Free article. No abstract available.
Effects of enrichment strategies on outcome of adrecizumab treatment in septic shock: Post-hoc analyses of the phase II adrenomedullin and outcome in septic shock 2 trial.
van Lier D, Picod A, Marx G, Laterre PF, Hartmann O, Knothe C, Azibani F, Struck J, Santos K, Zimmerman J, Bergmann A, Mebazaa A, Pickkers P. van Lier D, et al. Front Med (Lausanne). 2022 Dec 1;9:1058235. doi: 10.3389/fmed.2022.1058235. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36530868 Free PMC article.
37 results