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Anti-CD160, Alone or in Combination With Bevacizumab, Is a Potent Inhibitor of Ocular Neovascularization in Rabbit and Monkey Models.
Menguy T, Briaux A, Jeunesse E, Giustiniani J, Calcei A, Guyon T, Mizrahi J, Haegel H, Duong V, Soler V, Brousset P, Bensussan A, Raymond Letron I, Le Bouteiller P. Menguy T, et al. Among authors: giustiniani j. Invest Ophthalmol Vis Sci. 2018 Jun 1;59(7):2687-2698. doi: 10.1167/iovs.18-24024. Invest Ophthalmol Vis Sci. 2018. PMID: 29860455
Engagement of CD160 receptor by HLA-C is a triggering mechanism used by circulating natural killer (NK) cells to mediate cytotoxicity.
Le Bouteiller P, Barakonyi A, Giustiniani J, Lenfant F, Marie-Cardine A, Aguerre-Girr M, Rabot M, Hilgert I, Mami-Chouaib F, Tabiasco J, Boumsell L, Bensussan A. Le Bouteiller P, et al. Among authors: giustiniani j. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16963-8. doi: 10.1073/pnas.012681099. Epub 2002 Dec 16. Proc Natl Acad Sci U S A. 2002. PMID: 12486241 Free PMC article.
Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells.
Fons P, Chabot S, Cartwright JE, Lenfant F, L'Faqihi F, Giustiniani J, Herault JP, Gueguen G, Bono F, Savi P, Aguerre-Girr M, Fournel S, Malecaze F, Bensussan A, Plouët J, Le Bouteiller P. Fons P, et al. Among authors: giustiniani j. Blood. 2006 Oct 15;108(8):2608-15. doi: 10.1182/blood-2005-12-019919. Epub 2006 Jun 29. Blood. 2006. PMID: 16809620 Free article.
82 results