Dimitrov DS - Search Results

1

Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release.

Szot C, Saha S, Zhang XM, Zhu Z, Hilton MB, Morris K, Seaman S, Dunleavey JM, Hsu KS, Yu GJ, Morris H, Swing DA, Haines DC, Wang Y, Hwang J, Feng Y, Welsch D, DeCrescenzo G, Chaudhary A, Zudaire E, Dimitrov DS, St Croix B. Szot C, et al. Among authors: dimitrov ds. J Clin Invest. 2018 Jul 2;128(7):2927-2943. doi: 10.1172/JCI120481. Epub 2018 Jun 4. J Clin Invest. 2018. PMID: 29863500 Free PMC article.

2

Oligomerization of the SARS-CoV S glycoprotein: dimerization of the N-terminus and trimerization of the ectodomain.

Xiao X, Feng Y, Chakraborti S, Dimitrov DS. Xiao X, et al. Among authors: dimitrov ds. Biochem Biophys Res Commun. 2004 Sep 10;322(1):93-9. doi: 10.1016/j.bbrc.2004.07.084. Biochem Biophys Res Commun. 2004. PMID: 15313178 Free PMC article.

3

Novel human monoclonal antibodies to insulin-like growth factor (IGF)-II that potently inhibit the IGF receptor type I signal transduction function.

Feng Y, Zhu Z, Xiao X, Choudhry V, Barrett JC, Dimitrov DS. Feng Y, et al. Among authors: dimitrov ds. Mol Cancer Ther. 2006 Jan;5(1):114-20. doi: 10.1158/1535-7163.MCT-05-0252. Mol Cancer Ther. 2006. PMID: 16432169

4

Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody.

Prabakaran P, Gan J, Feng Y, Zhu Z, Choudhry V, Xiao X, Ji X, Dimitrov DS. Prabakaran P, et al. Among authors: dimitrov ds. J Biol Chem. 2006 Jun 9;281(23):15829-36. doi: 10.1074/jbc.M600697200. Epub 2006 Apr 5. J Biol Chem. 2006. PMID: 16597622 Free PMC article.

5

Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies.

Zhu Z, Chakraborti S, He Y, Roberts A, Sheahan T, Xiao X, Hensley LE, Prabakaran P, Rockx B, Sidorov IA, Corti D, Vogel L, Feng Y, Kim JO, Wang LF, Baric R, Lanzavecchia A, Curtis KM, Nabel GJ, Subbarao K, Jiang S, Dimitrov DS. Zhu Z, et al. Among authors: dimitrov ds. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12123-8. doi: 10.1073/pnas.0701000104. Epub 2007 Jul 9. Proc Natl Acad Sci U S A. 2007. PMID: 17620608 Free PMC article.

6

Exceptionally potent cross-reactive neutralization of Nipah and Hendra viruses by a human monoclonal antibody.

Zhu Z, Bossart KN, Bishop KA, Crameri G, Dimitrov AS, McEachern JA, Feng Y, Middleton D, Wang LF, Broder CC, Dimitrov DS. Zhu Z, et al. Among authors: dimitrov ds, dimitrov as. J Infect Dis. 2008 Mar 15;197(6):846-53. doi: 10.1086/528801. J Infect Dis. 2008. PMID: 18271743 Free PMC article.

7

Monoclonal antibodies against components of the IGF system for cancer treatment.

Feng Y, Dimitrov DS. Feng Y, et al. Among authors: dimitrov ds. Curr Opin Drug Discov Devel. 2008 Mar;11(2):178-85. Curr Opin Drug Discov Devel. 2008. PMID: 18283605 Review.

8

Construction of a large phage-displayed human antibody domain library with a scaffold based on a newly identified highly soluble, stable heavy chain variable domain.

Chen W, Zhu Z, Feng Y, Xiao X, Dimitrov DS. Chen W, et al. Among authors: dimitrov ds. J Mol Biol. 2008 Oct 10;382(3):779-89. doi: 10.1016/j.jmb.2008.07.054. Epub 2008 Jul 26. J Mol Biol. 2008. PMID: 18687338 Free PMC article.

9

Structure of an isolated unglycosylated antibody C(H)2 domain.

Prabakaran P, Vu BK, Gan J, Feng Y, Dimitrov DS, Ji X. Prabakaran P, et al. Among authors: dimitrov ds. Acta Crystallogr D Biol Crystallogr. 2008 Oct;64(Pt 10):1062-7. doi: 10.1107/S0907444908025274. Epub 2008 Sep 19. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18931413 Free PMC article.

10

Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers.

Chen W, Zhu Z, Feng Y, Dimitrov DS. Chen W, et al. Among authors: dimitrov ds. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17121-6. doi: 10.1073/pnas.0805297105. Epub 2008 Oct 28. Proc Natl Acad Sci U S A. 2008. PMID: 18957538 Free PMC article.

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