Zhou L - Search Results

1

Ubiquitin-conjugating enzyme UBE2O regulates cellular clock function by promoting the degradation of the transcription factor BMAL1.

Chen S, Yang J, Zhang Y, Duan C, Liu Q, Huang Z, Xu Y, Zhou L, Xu G. Chen S, et al. Among authors: zhou l. J Biol Chem. 2018 Jul 20;293(29):11296-11309. doi: 10.1074/jbc.RA117.001432. Epub 2018 Jun 5. J Biol Chem. 2018. PMID: 29871923 Free PMC article.

2

Cereblon suppresses the formation of pathogenic protein aggregates in a p62-dependent manner.

Zhou L, Hao Z, Wang G, Xu G. Zhou L, et al. Hum Mol Genet. 2018 Feb 15;27(4):667-678. doi: 10.1093/hmg/ddx433. Hum Mol Genet. 2018. PMID: 29272390

3

Deubiquitinating enzyme USP9X regulates cellular clock function by modulating the ubiquitination and degradation of a core circadian protein BMAL1.

Zhang Y, Duan C, Yang J, Chen S, Liu Q, Zhou L, Huang Z, Xu Y, Xu G. Zhang Y, et al. Among authors: zhou l. Biochem J. 2018 Apr 30;475(8):1507-1522. doi: 10.1042/BCJ20180005. Biochem J. 2018. PMID: 29626158

4

Cereblon suppresses the lipopolysaccharide-induced inflammatory response by promoting the ubiquitination and degradation of c-Jun.

Yang J, Huang M, Zhou L, He X, Jiang X, Zhang Y, Xu G. Yang J, et al. Among authors: zhou l. J Biol Chem. 2018 Jun 29;293(26):10141-10157. doi: 10.1074/jbc.RA118.002246. Epub 2018 May 10. J Biol Chem. 2018. PMID: 29748389 Free PMC article.

5

Ubiquitin ligase TRAF2 attenuates the transcriptional activity of the core clock protein BMAL1 and affects the maximal Per1 mRNA level of the circadian clock in cells.

Chen S, Yang J, Yang L, Zhang Y, Zhou L, Liu Q, Duan C, Mieres CA, Zhou G, Xu G. Chen S, et al. Among authors: zhou g, zhou l. FEBS J. 2018 Aug;285(16):2987-3001. doi: 10.1111/febs.14595. Epub 2018 Jul 5. FEBS J. 2018. PMID: 29935055 Free article.

6

Cereblon attenuates DNA damage-induced apoptosis by regulating the transcription-independent function of p53.

Zhou L, Xu G. Zhou L, et al. Cell Death Dis. 2019 Jan 25;10(2):69. doi: 10.1038/s41419-019-1317-7. Cell Death Dis. 2019. PMID: 30683842 Free PMC article.

7

Endoplasmic Reticulum Stress-Mediated p62 Downregulation Inhibits Apoptosis via c-Jun Upregulation.

Yu W, Wang B, Zhou L, Xu G. Yu W, et al. Among authors: zhou l. Biomol Ther (Seoul). 2021 Mar 1;29(2):195-204. doi: 10.4062/biomolther.2020.089. Biomol Ther (Seoul). 2021. PMID: 33046662 Free PMC article.

8

Caspase-8 Inhibition Prevents the Cleavage and Degradation of E3 Ligase Substrate Receptor Cereblon and Potentiates Its Biological Function.

Zhou L, Yu W, Jayabalan DS, Niesvizky R, Jaffrey SR, Huang X, Xu G. Zhou L, et al. Front Cell Dev Biol. 2020 Dec 17;8:605989. doi: 10.3389/fcell.2020.605989. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33392195 Free PMC article.

9

Caspase-8 Regulates the Antimyeloma Activity of Bortezomib and Lenalidomide.

Zhou L, Huang X, Niesvizky R, Pu Z, Xu G. Zhou L, et al. J Pharmacol Exp Ther. 2021 Dec;379(3):303-309. doi: 10.1124/jpet.121.000818. Epub 2021 Sep 29. J Pharmacol Exp Ther. 2021. PMID: 34588172

10

The Ubiquitination-Dependent and -Independent Functions of Cereblon in Cancer and Neurological Diseases.

Zhou L, Xu G. Zhou L, et al. J Mol Biol. 2022 Mar 15;434(5):167457. doi: 10.1016/j.jmb.2022.167457. Epub 2022 Jan 16. J Mol Biol. 2022. PMID: 35045330 Review.

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